Rome2Rio

How to get fromPittsburgh to Louisville, KYby bus (Greyhound), car, plane, bus (Flixbus, Greyhound), or bus

Find Transport to Louisville, KY

See all options

There are 9 ways to get from Pittsburgh to Louisville, KY by bus (Greyhound), car, plane, bus (Flixbus, Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus Greyhound US0421
    2. Take the bus from Columbus to Louisvillebus bus Bsb 27
    8h 35m
    $67–107

  2. Bus via Columbus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbusbus bus Greyhound US0421
    2. Take the bus from Columbus to Louisvillebus bus Bsb 27
    9h 5m
    $54–110

  3. Drive  386.7 mi

    1. Drive from Pittsburgh to Louisville, KYcar car 386.7 mi
    6h 38m
    $71–102

  4. Fly Pittsburgh International Airport to Blue Grass Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Blue Grass Airport (LEX)plane plane PIT - LEX
    2. Drive from Lexington-Airport-LEX to Louisville, KYcar car
    7h 21m
    $89–459

  5. Bus #2

    1. Take the bus from Pittsburgh Intermodal Station to Cincinnatibus bus FlixBus N2642
    2. Take the bus from Covington Bus Stop to Louisville Bus Stationbus bus Greyhound US0135
    9h 41m
    $68–103

  6. Bus to Pittsburgh International Airport, fly to Louisville International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane plane PIT - SDF
    5h 19m

  7. Bus to Morgantown Municipal Airport, fly to Louisville International Airport

    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Fly from Morgantown Municipal Airport (MGW) to Louisville International Airport (SDF)plane plane MGW - SDF
    9h 54m
    $115–734

  8. Fly Pittsburgh International Airport to Nashville, bus

    1. Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane plane PIT - BNA
    2. Take the bus from Nashville Bus Station to Louisville Bus Stationbus bus
    8h 34m
    $515–1,127

  9. Fly Pittsburgh International Airport to Covington, bus

    1. Fly from Pittsburgh International Airport (PIT) to Covington (CVG)plane plane PIT - CVG
    2. Take the bus from Covington Bus Stop to Louisville Bus Stationbus bus
    9h 45m
    $142–754

Pittsburgh to Louisville, KY by bus

Calendar14Weekly Buses
Duration8h 35mAverage Duration
Ticket$67Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Pittsburgh to Louisville, KY.ExpandLaunch map view
  • Distance: 397.8 mi
  • Duration: 8h 35m

What companies run services between Pittsburgh, PA, USA and Louisville, KY, USA?

You can take a bus from Pittsburgh Intermodal Station to Louisville via Columbus in around 8h 35m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There