There are 6 ways to get from Pittsburgh to Louisville, KY by bus (Greyhound), car, bus, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Pittsburgh Intermodal Station to Columbusbus Greyhound US0421
- Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus Cleveland
8h 45m$59–120Bus via Columbus
cheapest- Take the bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbusbus Greyhound US0421
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus Cleveland
9h 10m$50–117Drive 386.7 mi
- Drive from Pittsburgh to Louisville, KYcar 386.7 mi
6h 38m$71–102Bus, fly to Louisville International Airport
- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane PIT - SDF
5h 25mBus #2
- Take the bus from Pittsburgh Intermodal Station to Cincinnatibus FlixBus N2642
- Take the bus from Cincinnati to Louisvillebus Bsb 27
9h 40m$61–131Fly to Nashville, bus
- Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane PIT - BNA
- Take the bus from Nashville Bus Station to Louisville Bus Stationbus
7h 54m$668–1,070
Pittsburgh to Louisville, KY by bus
Questions & Answers
The cheapest way to get from Pittsburgh to Louisville, KY is to bus via Columbus which costs $50 - $120 and takes 9h 10m.
The fastest way to get from Pittsburgh to Louisville, KY is to drive which takes 6h 38m and costs $70 - $110.
No, there is no direct bus from Pittsburgh station to Louisville, KY station. However, there are services departing from Pittsburgh Intermodal Station and arriving at Louisville, KY Bus Station via Columbus - Downtown - Mound St. The journey, including transfers, takes approximately 8h 45m.
The distance between Pittsburgh and Louisville, KY is 400 miles. The road distance is 389 miles.
The best way to get from Pittsburgh to Louisville, KY without a car is to bus which takes 8h 45m and costs $55 - $120.
It takes approximately 8h 45m to get from Pittsburgh to Louisville, KY, including transfers.
Pittsburgh to Louisville, KY bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Louisville, KY bus services, operated by Greyhound USA, arrive at Columbus station.
Yes, the driving distance between Pittsburgh to Louisville, KY is 389 miles. It takes approximately 6h 38m to drive from Pittsburgh to Louisville, KY.
Book your Pittsburgh to Louisville, KY bus tickets online with Omio and FlixBus.
What companies run services between Pittsburgh, PA, USA and Louisville, KY, USA?
You can take a bus from Pittsburgh Intermodal Station to Louisville, KY Bus Station via Columbus - Downtown - Mound St in around 8h 45m.
- Website
- southwest.com
Flights from Pittsburgh International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 3h 20m
- When
- Saturday
- Estimated price
- $110–600
Flights from Pittsburgh International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 45m
- When
- Sunday
- Estimated price
- $120–650
Flights from Pittsburgh International Airport to Nashville
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $75–430
Flights from Pittsburgh International Airport to Nashville via Chicago Midway
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $100–550
- Website
- delta.com
Flights from Pittsburgh International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 3h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Pittsburgh International Airport to Nashville via Detroit
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $90–480
Flights from Pittsburgh International Airport to Nashville via Atlanta
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $100–500
- Website
- allegiantair.com
Flights from Pittsburgh International Airport to Nashville
- Ave. Duration
- 1h 36m
- When
- Thursday and Sunday
- Estimated price
- $75–430
- Website
- flybreeze.com
Flights from Pittsburgh International Airport to Louisville International Airport
- Ave. Duration
- 1h 29m
- When
- Thursday and Sunday
- Estimated price
- $210–1,500
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Pittsburgh Intermodal Station to Columbus
- Ave. Duration
- 3h 10m
- Frequency
- 3 times a day
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
Bus from Columbus - Downtown - Mound St to Louisville, KY Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbus
- Ave. Duration
- 4h 5m
- Frequency
- 3 times a day
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Nashville Bus Station to Louisville Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Every 4 hours
- Estimated price
- $27–55
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Pittsburgh Intermodal Station to Columbus
- Ave. Duration
- 3h 10m
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
Bus from Columbus - Downtown - Mound St to Louisville, KY Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbus
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
Bus from Nashville Bus Station to Louisville Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Schedules at
- greyhound.com
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Columbus - Downtown - Mound St to Louisville, KY Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $21–60
- Website
- https://baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Station
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- https://baronsbus.com
Bus from Cincinnati to Louisville
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Website
- example.com
Bus from Columbus - Downtown - Mound St to Louisville, KY Bus Station
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Schedules at
- example.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Station
- Ave. Duration
- 4h
- Frequency
- Once daily
- Schedules at
- example.com
Bus from Cincinnati to Louisville
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Schedules at
- example.com
- Phone
- +1 412-442-2000
- Website
- rideprt.org
Bus from Seventh Ave + Smithfield St to Pittsburgh International Airport
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Website
- https://www.rideprt.org
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Pittsburgh Intermodal Station to Cincinnati
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a week
- Estimated price
- $50–85
- Schedules at
- flixbus.com
Bus from Nashville Bus Station to Louisville Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $28–50
- Schedules at
- flixbus.com
- Website
- flixbus.com
Bus from Nashville Bus Station to Louisville Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville Bus Station to Louisville Bus Station
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
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