There are 5 ways to get from Pittsburgh to Mesa by plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Pittsburgh International Airport
best- Fly from Pittsburgh International Airport (PIT) to Phoenix (PHX)plane PIT - PHX
7h 34m$170–722Bus (Greyhound)
- Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus Greyhound US0421
- Take the bus from St Louis Bus Station to Phoenix Bus Stationbus Greyhound US1210
45h 13m$382–574Train, bus
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Flagstafftrain
- Take the bus from Flagstaff Train Station to Tempebus
46h 53m$1,189–1,945Drive 2,037.4 mi
- Drive from Pittsburgh to Mesacar 2,037.4 mi
33h 12m$372–538Train to Cleveland-Hopkins International Airport, fly
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Fly from Cleveland-Hopkins International Airport (CLE) to Phoenix (PHX)plane CLE - PHX
10h 16m$251–671
Pittsburgh to Mesa by bus and tram (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Mesa is to train and fly which costs $250 - $700 and takes 10h 16m.
The fastest way to get from Pittsburgh to Mesa is to fly which takes 7h 34m and costs $170 - $750.
No, there is no direct bus from Pittsburgh station to Mesa station. However, there are services departing from Pittsburgh Intermodal Station and arriving at Phoenix Bus Station via St Louis Bus Station. The journey, including transfers, takes approximately 45h 13m.
The distance between Pittsburgh and Mesa is 1857 miles. The road distance is 2049.3 miles.
The best way to get from Pittsburgh to Mesa without a car is to bus which takes 45h 13m and costs $380 - $600.
It takes approximately 7h 34m to get from Pittsburgh to Mesa, including transfers.
Pittsburgh to Mesa bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
The best way to get from Pittsburgh to Mesa is to fly which takes 7h 34m and costs $170 - $750. Alternatively, you can bus, which costs $380 - $600 and takes 45h 13m.
Pittsburgh to Mesa bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Mesa is 3h behind Pittsburgh. It is currently 10:11 PM in Pittsburgh and 7:11 PM in Mesa.
What companies run services between Pittsburgh, PA, USA and Mesa, AZ, USA?
American Airlines, Southwest Airlines, and two other airlines fly from Pittsburgh International Airport (PIT) to Phoenix (PHX) every 4 hours. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Mesa Dr/Main St via St Louis Bus Station, Phoenix, Bus Station (E Buckeye Rd), 24th St Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, and 44th St/Washington in around 45h 13m.
- Website
- southwest.com
Flights from Pittsburgh International Airport to Phoenix
- Ave. Duration
- 4h 42m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–750
Flights from Pittsburgh International Airport to Phoenix via Chicago Midway
- Ave. Duration
- 6h 26m
- When
- Saturday, Tuesday, Wednesday, Monday, and Sunday
- Estimated price
- $170–750
Flights from Pittsburgh International Airport to Phoenix via Denver
- Ave. Duration
- 6h 37m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $170–750
Flights from Pittsburgh International Airport to Phoenix via Nashville
- Ave. Duration
- 6h 42m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $170–750
Flights from Pittsburgh International Airport to Phoenix via St. Louis
- Ave. Duration
- 6h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–750
Flights from Cleveland-Hopkins International Airport to Phoenix
- Ave. Duration
- 4h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–750
Flights from Cleveland-Hopkins International Airport to Phoenix via St. Louis
- Ave. Duration
- 6h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–750
Flights from Cleveland-Hopkins International Airport to Phoenix via Chicago Midway
- Ave. Duration
- 6h 13m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $160–750
Flights from Cleveland-Hopkins International Airport to Phoenix via Denver
- Ave. Duration
- 6h 30m
- When
- Saturday
- Estimated price
- $160–750
Flights from Cleveland-Hopkins International Airport to Phoenix via Nashville
- Ave. Duration
- 6h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $170–750
- Website
- aa.com
Flights from Pittsburgh International Airport to Phoenix
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $160–750
Flights from Cleveland-Hopkins International Airport to Phoenix
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $160–750
- Website
- delta.com
Flights from Pittsburgh International Airport to Phoenix via Detroit
- Ave. Duration
- 6h 42m
- When
- Saturday
- Estimated price
- $170–750
Flights from Cleveland-Hopkins International Airport to Phoenix via Detroit
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $160–750
- Website
- united.com
Flights from Pittsburgh International Airport to Phoenix via Denver
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $170–750
Flights from Cleveland-Hopkins International Airport to Phoenix via Denver
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $160–750
- Website
- flyfrontier.com
Flights from Cleveland-Hopkins International Airport to Phoenix
- Ave. Duration
- 4h 43m
- When
- Thursday and Friday
- Estimated price
- $170–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $260–410
- Website
- Amtrak
Train from Chicago Union Station to Flagstaff
- Ave. Duration
- 31h 44m
- Frequency
- Once daily
- Estimated price
- $900–1,500
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to St Louis Bus Station
- Ave. Duration
- 13h 10m
- Frequency
- 3 times a day
- Estimated price
- $110–170
- Website
- Greyhound
Bus from St Louis Bus Station to Phoenix Bus Station
- Ave. Duration
- 30h
- Frequency
- Twice daily
- Estimated price
- $270–410
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Flagstaff Train Station to Tempe
- Ave. Duration
- 2h 50m
- Frequency
- 5 times a week
- Estimated price
- $24–40
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Pittsburgh to Mesa is 2049 miles. It takes approximately 33h 12m to drive from Pittsburgh to Mesa.
Book your Pittsburgh to Mesa bus tickets online with Omio.
There are 2831+ hotels available in Mesa.






