There are 8 ways to get from Pittsburgh to Mississauga by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Pittsburgh International Airport, fly to Toronto Pearson International Airport
best- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Toronto Pearson International Airport (YYZ)plane PIT - YYZ
4h 55mBus
cheapest- Take the bus from Pittsburgh Intermodal Station to Eriebus Greyhound US0440s
- Take the bus from Erie to Torontobus FlixBus 2526
10h 22m$78–126Bus via Buffalo
- Take the bus from Pittsburgh Intermodal Station to Eriebus
- Take the bus from Erie, PA to Buffalo, NYbus
- Take the bus from Buffalo to Mississaugabus
9h 21m$82–168Train
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Take the train from Cleveland Amtrak to Buffalo Depew Stationtrain
- Take the train from Buffalo to Oakvilletrain
12h 28m$166–514Drive 482.5 km
- Drive from Pittsburgh to Mississaugacar 482.5 km
5h 14m$98–141Fly Pittsburgh International Airport to Toronto Island Airport
- Fly from Pittsburgh International Airport (PIT) to Toronto Island Airport (YTZ)plane PIT - YTZ
8h 27m$370–1,075Train to Cleveland-Hopkins International Airport, fly to Toronto Pearson International Airport
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Fly from Cleveland-Hopkins International Airport (CLE) to Toronto Pearson International Airport (YYZ)plane CLE - YYZ
7h 37m$761–1,824Bus #2
- Take the bus from Pittsburgh to Buffalobus Fab510
- Take the bus from Buffalo to Torontobus FlixBus 2685 / ...
13h 37m$134–395
Pittsburgh to Mississauga by bus
Questions & Answers
The cheapest way to get from Pittsburgh to Mississauga is to bus which costs $75 - $130 and takes 10h 22m.
The fastest way to get from Pittsburgh to Mississauga is to drive which takes 5h 14m and costs $95 - $140.
No, there is no direct bus from Pittsburgh station to Mississauga. However, there are services departing from Pittsburgh Intermodal Station and arriving at City Centre Transit Terminal Platform A via Erie, PA, Buffalo and Winston Churchill Station East Platform 6. The journey, including transfers, takes approximately 9h 21m.
No, there is no direct train from Pittsburgh station to Mississauga. However, there are services departing from Pittsburgh Amtrak Station and arriving at Clarkson GO via Cleveland Amtrak, Buffalo and Oakville GO. The journey, including transfers, takes approximately 12h 28m.
The distance between Pittsburgh and Mississauga is 414 km. The road distance is 482.5 km.
The best way to get from Pittsburgh to Mississauga without a car is to bus via Buffalo which takes 9h 21m and costs $80 - $170.
It takes approximately 4h 55m to get from Pittsburgh to Mississauga, including transfers.
Pittsburgh to Mississauga bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Mississauga train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Mississauga is to bus via Buffalo which takes 9h 21m and costs $80 - $170. Alternatively, you can train, which costs $160 - $550 and takes 12h 28m, you could also fly, which costs $370 - $1,100 and takes 8h 27m.
What companies run services between Pittsburgh, PA, USA and Mississauga, ON, Canada?
You can take a bus from Pittsburgh Intermodal Station to City Centre Transit Terminal Platform A via Erie, Erie, PA, Buffalo, and Winston Churchill Station East Platform 6 in around 9h 21m. Alternatively, you can take a train from Pittsburgh Amtrak Station to University Of Toronto At Mississauga Campus via Cleveland Amtrak, Buffalo, Oakville, Oakville GO, Clarkson GO, and Clarkson Go Station Platform 9 in around 12h 28m.
- Website
- aircanada.com
Flights from Pittsburgh International Airport to Toronto Pearson International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $65–470
Flights from Pittsburgh International Airport to Toronto Island Airport via Montreal
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Pittsburgh International Airport to Toronto Island Airport via Chicago O'Hare
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $130–700
Flights from Pittsburgh International Airport to Toronto Island Airport via New York La Guardia
- Ave. Duration
- 4h 12m
- When
- Monday to Saturday
- Estimated price
- $110–650
Flights from Cleveland-Hopkins International Airport to Toronto Pearson International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $65–460
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $50–120
- Website
- Amtrak
Train from Cleveland Amtrak to Buffalo Depew Station
- Ave. Duration
- 3h 3m
- Frequency
- Twice daily
- Estimated price
- $70–160
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $50–120
- Website
- Amtrak
- Phone
- +1 412-442-2000
- Website
- Pittsburgh Regional Transit
Bus from Seventh Ave + Smithfield St to Pittsburgh International Airport
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
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More Questions & Answers
Pittsburgh to Mississauga bus services, operated by Greyhound USA, arrive at Erie station.
Pittsburgh to Mississauga train services, operated by Amtrak, arrive at Cleveland Amtrak station.
Yes, the driving distance between Pittsburgh to Mississauga is 483 km. It takes approximately 5h 14m to drive from Pittsburgh to Mississauga.
Book your Pittsburgh to Mississauga bus tickets online with Omio.
There are 1867+ hotels available in Mississauga.



