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How to get fromPittsburgh to Mississaugaby bus, plane, bus (Greyhound), train (Amtrak), car, train, bus (Flixbus, Greyhound), or bus (Flixbus)

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There are 8 ways to get from Pittsburgh to Mississauga by bus, plane, bus (Greyhound), train (Amtrak), car, train, bus (Flixbus, Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Toronto Pearson International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Toronto Pearson International Airport (YYZ)plane plane PIT - YYZ
    4h 56m

  2. Bus via Erie

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Eriebus bus
    2. Take the bus from Erie, PA to Buffalo, NYbus bus
    3. Take the bus from Buffalo to Mississaugabus bus
    9h 21m
    $81–172

  3. Train

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Take the train from Cleveland Amtrak to Buffalo Depew Stationtrain train
    3. Take the train from Buffalo to Toronto Union Stationtrain train
    13h 46m
    $196–546

  4. Drive 482.5 km

    1. Drive from Pittsburgh to Mississaugacar car 482.5 km
    5h 14m
    $96–139

  5. Fly Pittsburgh International Airport to Toronto Island Airport

    1. Fly from Pittsburgh International Airport (PIT) to Toronto Island Airport (YTZ)plane plane PIT - YTZ
    8h 26m
    $362–985

  6. Train to Cleveland-Hopkins International Airport, fly to Toronto Pearson International Airport

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Toronto Pearson International Airport (YYZ)plane plane CLE - YYZ
    7h 35m
    $722–1,936

  7. Bus

    1. Take the bus from Pittsburgh to Buffalobus bus Fab510
    2. Take the bus from Buffalo to Torontobus bus Adt N816 / ...
    13h 3m
    $175–317

  8. Bus #2

    1. Take the bus from Pittsburgh to Buffalobus bus Fab510
    2. Take the bus from Buffalo to Toronto Pearson Airportbus bus FlixBus N2687
    13h 20m
    $172–307

Pittsburgh to Mississauga by bus

Calendar7Weekly Buses
Duration9h 21mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Mississauga.ExpandLaunch map view
  • Distance: 413.8 km
  • Duration: 4h 56m

What companies run services between Pittsburgh, PA, USA and Mississauga, ON, Canada?

You can take a bus from Pittsburgh Intermodal Station to City Centre Transit Terminal Platform A via Erie, Erie, PA, Buffalo, and Winston Churchill Station East Platform 6 in around 9h 21m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Erindale GO via Cleveland Amtrak, Buffalo, and Union Station GO in around 13h 46m.

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