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How to get fromPittsburgh to Mississippiby plane, bus (Greyhound), train (Amtrak), car, bus, or train

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There are 7 ways to get from Pittsburgh to Mississippi by plane, bus (Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Memphis

    best
    1. Fly from Pittsburgh International Airport (PIT) to Memphis (MEM)plane plane PIT - MEM
    5h 53m
    $169–773

  2. Fly to Jackson/Vicksburg

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Jackson/Vicksburg (JAN)plane plane PIT - JAN
    6h 45m
    $136–515

  3. Bus (Greyhound)

    1. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Jacksonbus bus Greyhound US1173
    25h 40m
    $176–329

  4. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to Jacksontrain train City of New Orleans
    26h 21m
    $397–815

  5. Drive 945.8 mi

    1. Drive from Pittsburgh to Jacksoncar car 945.8 mi
    16h 47m
    $173–250

  6. Fly to Gulfport-Biloxi Regional Airport

    1. Fly from Pittsburgh International Airport (PIT) to Gulfport-Biloxi Regional Airport (GPT)plane plane PIT - GPT
    6h 21m
    $325–768

  7. Bus, train

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    2. Take the train from Homewood to Jacksontrain train City of New Orleans
    28h 37m
    $317–622

Pittsburgh to Mississippi by bus (Greyhound)

Calendar7Weekly Buses
Duration25h 40mAverage Duration
Ticket$176Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Mississippi.ExpandLaunch map view
  • Distance: 683 mi
  • Duration: 5h 53m

What companies run services between Pittsburgh, PA, USA and Mississippi, USA?

Southwest Airlines, Delta, and American Airlines fly from Pittsburgh International Airport (PIT) to Memphis (MEM) every 2 hours. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Jackson via St Louis Bus Station in around 25h 40m.

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