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How to get fromPittsburgh to Mount Pleasantby bus, plane, train (Amtrak), car, or train

Find Transport to Mount Pleasant

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There are 7 ways to get from Pittsburgh to Mount Pleasant by bus, plane, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly, line 41 bus

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane plane PIT - CHS
    3. Take the bus from Mary St / Meeting St to Coleman Blvd / Chuck Dawley Blvdbus bus
    6h 54m

  2. Drive 650.4 mi

    cheapest
    1. Drive from Pittsburgh to Mount Pleasantcar car 650.4 mi
    11h 14m
    $119–172

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    18h 58m
    $290–583

  4. Bus, drive

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Norfolkbus bus
    3. Take the bus from Norfolk to Myrtle Beach Bus Stationbus bus
    4. Drive from Myrtle Beach Bus Station to S. Pinckney St / Society Rdcar car
    5. Take the bus from S. Pinckney St / Society Rd to East Cooper Medical Centerbus bus
    24h 25m
    $133–258

  5. Bus to Akron, fly

    1. Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Charleston International Airport (CHS)plane plane CAK - CHS
    9h 34m
    $132–287

  6. Train, bus, drive via Richmond

    1. Take the train from Pittsburgh Amtrak Station to Richmond Staples Mill Road Amtrak Stationtrain train
    2. Take the train from Richmond Staples Mill Road Amtrak Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    4. Drive from Myrtle Beach Bus Station to S. Pinckney St / Society Rdcar car
    5. Take the bus from S. Pinckney St / Society Rd to Stuart Engals Blvd / Wando Crossing Centerbus bus
    28h 40m
    $267–553

  7. Train, bus, drive

    1. Take the train from Pittsburgh Amtrak Station to Raleigh Union Stationtrain train
    2. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    3. Drive from Myrtle Beach Bus Station to S. Pinckney St / Society Rdcar car
    4. Take the bus from S. Pinckney St / Society Rd to Stuart Engals Blvd / Wando Crossing Centerbus bus
    29h 28m
    $281–564

Pittsburgh International Airport (PIT) to Charleston International Airport (CHS) flights

Calendar60Weekly Planes
Duration3h 24mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Mount Pleasant.ExpandLaunch map view
  • Distance: 573.3 mi
  • Duration: 6h 54m

What companies run services between Pittsburgh, PA, USA and Mount Pleasant, SC, USA?

You can take a train from Pittsburgh Amtrak Station to Mount Pleasant via Petersburg Amtrak Station and Charleston Amtrak Station in around 18h 58m.

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Bus operators

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