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How to get fromPittsburgh to North Carolinaby bus, plane, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

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There are 7 ways to get from Pittsburgh to North Carolina by bus, plane, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Charlotte Douglas International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Charlotte Douglas International Airport (CLT)plane plane PIT - CLT
    4h 25m

  2. Bus via Charleston

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    11h 50m
    $70–162

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Carytrain train Floridian
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train Piedmont / ...
    19h 5m
    $249–505

  4. Drive 442.3 mi

    1. Drive from Pittsburgh to Charlottecar car 442.3 mi
    7h 39m
    $81–117

  5. Bus to Pittsburgh International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Raleigh-Durham International Airport (RDU)plane plane PIT - RDU
    5h 4m

  6. Drive to Altoona–Blair County Airport, fly to Charlotte Douglas International Airport

    1. Drive from Pittsburgh to Altoona–Blair County Airport (AOO)car car
    2. Fly from Altoona–Blair County Airport (AOO) to Charlotte Douglas International Airport (CLT)plane plane AOO - CLT
    4h 45m
    $121–240

  7. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus FlixBus N2640 / ...
    2. Take the bus from Columbus to Charlottebus bus Bsb 32
    16h 12m

Pittsburgh to North Carolina by bus

Calendar14Weekly Buses
Duration11h 50mAverage Duration
Ticket$70Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to North Carolina.ExpandLaunch map view
  • Distance: 399.3 mi
  • Duration: 4h 25m

What companies run services between Pittsburgh, PA, USA and North Carolina, USA?

You can take a bus from Pittsburgh Intermodal Station to Charlotte Bus Station via Cambridge, OH, Cambridge, and Charleston, WV in around 11h 50m. Alternatively, you can take a train from Pittsburgh Amtrak Station to CTC Station via Cary, Charlotte Amtrak Station, and Parkwood Station in around 19h 5m.

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