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How to get fromPittsburgh to Orangeburgby plane, taxi, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

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There are 8 ways to get from Pittsburgh to Orangeburg by plane, taxi, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbia, taxi

    best
    1. Fly from Pittsburgh International Airport (PIT) to Columbia (CAE)plane plane PIT - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    6h 29m
    $288–1,085

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    16h 53m
    $104–222

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Denmark Amtrak Stationtrain train Floridian
    20h 37m
    $342–635

  4. Drive 575.3 mi

    1. Drive from Pittsburgh to Orangeburgcar car 575.3 mi
    9h 59m
    $105–152

  5. Fly to Savannah, train

    1. Fly from Pittsburgh International Airport (PIT) to Savannah (SAV)plane plane PIT - SAV
    2. Take the train from Savannah Station to Denmark Amtrak Stationtrain train
    7h 5m
    $240–752

  6. Fly to Myrtle Beach, bus

    1. Fly from Pittsburgh International Airport (PIT) to Myrtle Beach (MYR)plane plane PIT - MYR
    2. Take the bus from Myrtle Beach Bus Station to Orangeburgbus bus
    8h 37m
    $326–833

  7. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Charlotte Douglas International Airport (CLT)plane plane PIT - CLT
    2. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    9h 33m
    $131–611

  8. Bus, fly to Charleston International Airport, line 104 bus

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane plane PIT - CHS
    3. Take the bus from N. Charleston SuperStop to North Charleston Transit Centerbus bus
    4. Take the bus from Charleston Bus Station to Orangeburgbus bus
    8h 26m

Pittsburgh International Airport (PIT) to Columbia (CAE) flights

Calendar155Weekly Planes
Duration5h 14mAverage Duration
Ticket$167Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Orangeburg.ExpandLaunch map view
  • Distance: 519.8 mi
  • Duration: 6h 29m

What companies run services between Pittsburgh, PA, USA and Orangeburg, SC, USA?

You can take a bus from Pittsburgh Intermodal Station to Orangeburg via Cambridge, OH, Cambridge, Charleston, WV, Charlotte Bus Station, and Orangeburg in around 16h 53m. Alternatively, Amtrak operates a train from Pittsburgh Amtrak Station to Denmark Amtrak Station once daily. Tickets cost $270–600 and the journey takes 20h 5m.

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