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How to get fromPittsburgh to Orangeburgby plane, car, bus (Greyhound, Flixbus), train (Amtrak), taxi, or bus

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There are 6 ways to get from Pittsburgh to Orangeburg by plane, car, bus (Greyhound, Flixbus), train (Amtrak), taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charleston International Airport, drive

    best
    1. Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane plane PIT - CHS
    2. Drive from Charleston-Airport-CHS to Orangeburgcar car
    5h 10m
    $105–553

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charlestonbus bus
    3. Take the bus from Charleston to Charlottebus bus
    4. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    15h 28m
    $98–192

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Denmark Amtrak Stationtrain train Floridian
    20h 37m
    $530–793

  4. Drive  575.3 mi

    1. Drive from Pittsburgh to Orangeburgcar car 575.3 mi
    9h 59m
    $105–152

  5. Fly to Columbia, taxi

    1. Fly from Pittsburgh International Airport (PIT) to Columbia (CAE)plane plane PIT - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    6h 22m
    $191–573

  6. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Charlotte Douglas International Airport (CLT)plane plane PIT - CLT
    2. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    8h 6m
    $126–639

Pittsburgh International Airport (PIT) to Charleston International Airport (CHS) flights

Calendar55Weekly Planes
Duration3h 42mAverage Duration
Ticket$93Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Orangeburg.ExpandLaunch map view
  • Distance: 621.1 mi
  • Duration: 5h 10m

What companies run services between Pittsburgh, PA, USA and Orangeburg, SC, USA?

You can take a bus from Pittsburgh Intermodal Station to Orangeburg via Cambridge, Charleston, Charlotte Bus Station, and Orangeburg in around 15h 28m. Alternatively, Amtrak operates a train from Pittsburgh Amtrak Station to Denmark Amtrak Station once daily. Tickets cost $460–750 and the journey takes 20h 5m.

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