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How to get fromPittsburgh to Saint Louis Countyby bus, plane, bus (Greyhound), train (Amtrak), car, or train

Find Transport to Saint Louis County

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There are 5 ways to get from Pittsburgh to Saint Louis County by bus, plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    5h 17m

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    14h 41m
    $96–176

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    17h 10m
    $241–508

  4. Drive 613 mi

    1. Drive from Pittsburgh to Saint Louis Countycar car 613 mi
    10h 24m
    $112–162

  5. Train to Cleveland-Hopkins International Airport, fly

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    7h 52m
    $541–998

Pittsburgh to Saint Louis County by bus and train (Greyhound)

Calendar42Weekly Services
Duration14h 41mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Saint Louis County.ExpandLaunch map view
  • Distance: 596 mi
  • Duration: 5h 17m

What companies run services between Pittsburgh, PA, USA and Saint Louis County, MO, USA?

Greyhound USA operates a bus from Pittsburgh Intermodal Station to St Louis Bus Station every 4 hours. Tickets cost $90–180 and the journey takes 12h 55m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Clayton @ Devondale Place Wb via Chicago Union Station, St. Louis, CIVIC CENTER station, CLAYTON station, and Clayton Transit Center in around 17h 10m.

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