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How to get fromPittsburgh to Santeeby plane, car, bus (Greyhound, Flixbus), train, or taxi

Find Transport to Santee

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There are 5 ways to get from Pittsburgh to Santee by plane, car, bus (Greyhound, Flixbus), train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charleston International Airport, drive

    best
    1. Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane plane PIT - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    5h 2m
    $105–556

  2. Fly to Columbia, drive

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Columbia (CAE)plane plane PIT - CAE
    2. Drive from Columbia-Airport-CAE to Santeecar car
    6h 40m
    $83–446

  3. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charlestonbus bus
    3. Take the bus from Charleston to Charlottebus bus
    4. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    15h 53m
    $178–288

  4. Train, taxi (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Denmark Amtrak Stationtrain train Floridian
    2. Take the taxi from Denmark Amtrak Station to Santeetaxi taxi
    21h 2m
    $608–898

  5. Drive  594.1 mi

    1. Drive from Pittsburgh to Santeecar car 594.1 mi
    10h 18m
    $109–157

Pittsburgh International Airport (PIT) to Charleston International Airport (CHS) flights

Calendar49Weekly Planes
Duration3h 37mAverage Duration
Ticket$94Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Santee.ExpandLaunch map view
  • Distance: 610.7 mi
  • Duration: 5h 2m

What companies run services between Pittsburgh, PA, USA and Santee, SC, USA?

You can take a bus from Pittsburgh Intermodal Station to Santee via Cambridge, Charleston, Charlotte Bus Station, and Orangeburg in around 15h 53m.

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