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How to get fromPittsburgh to Senecaby plane, taxi, bus, train, car, or train (Amtrak)

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There are 7 ways to get from Pittsburgh to Seneca by plane, taxi, bus, train, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    4h 51m
    $243–841

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Asheville Regional Airport (AVL)plane plane PIT - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    7h 30m
    $85–449

  3. Bus, train via Charleston

    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Take the bus from Morgantown Mt Line to Charlestonbus bus
    3. Take the bus from Charleston to Charlottebus bus
    4. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train
    17h 21m
    $164–311

  4. Bus, train

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the train from Washington Union Station to Clemson Amtrak Stationtrain train Crescent
    17h 54m
    $342–533

  5. Drive  541.4 mi

    1. Drive from Pittsburgh to Senecacar car 541.4 mi
    10h 17m
    $99–143

  6. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Washington Union Stationtrain train Floridian
    2. Take the train from Washington Union Station to Clemson Amtrak Stationtrain train Crescent
    20h 34m
    $465–717

  7. Bus, taxi

    1. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus
    2. Take the bus from Columbus to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Flying J - Commercebus bus
    4. Take the taxi from Flying J - Commerce to Senecataxi taxi
    26h 45m
    $265–403

Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP) flights

Calendar54Weekly Planes
Duration3h 21mAverage Duration
Ticket$112Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Seneca.ExpandLaunch map view
  • Distance: 476.6 mi
  • Duration: 4h 51m

What companies run services between Pittsburgh, PA, USA and Seneca, SC, USA?

You can take a train from Pittsburgh Amtrak Station to Seneca via Washington Union Station and Clemson Amtrak Station in around 20h 34m.

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