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How to get fromPittsburgh to Senecaby plane, taxi, bus, car, or train (Amtrak)

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There are 5 ways to get from Pittsburgh to Seneca by plane, taxi, bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    4h 46m
    $232–742

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Asheville Regional Airport (AVL)plane plane PIT - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    7h 34m
    $81–403

  3. Bus, drive

    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charleston, WVbus bus
    3. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from WNC Ag Center Park-n-Ride to Senecacar car
    18h 37m
    $101–222

  4. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Washington Union Stationtrain train Floridian
    2. Take the train from Washington Union Station to Clemson Amtrak Stationtrain train Crescent
    20h 34m
    $279–560

  5. Drive 541.4 mi

    1. Drive from Pittsburgh to Senecacar car 541.4 mi
    10h 17m
    $99–143

Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP) flights

Calendar53Weekly Planes
Duration3h 27mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Seneca.ExpandLaunch map view
  • Distance: 476.6 mi
  • Duration: 4h 46m

What companies run services between Pittsburgh, PA, USA and Seneca, SC, USA?

You can take a train from Pittsburgh Amtrak Station to Seneca via Washington Union Station and Clemson Amtrak Station in around 20h 34m.

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