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How to get fromPittsburgh to Senecaby plane, taxi, bus, train, car, or train (Amtrak)

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There are 7 ways to get from Pittsburgh to Seneca by plane, taxi, bus, train, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    4h 50m
    $246–860

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Asheville Regional Airport (AVL)plane plane PIT - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    7h 39m
    $86–456

  3. Bus, train via Charleston

    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Take the bus from Morgantown Mt Line to Charlestonbus bus
    3. Take the bus from Charleston to Charlottebus bus
    4. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train
    17h 22m
    $145–311

  4. Bus, train

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the train from Washington Union Station to Clemson Amtrak Stationtrain train Crescent
    17h 54m
    $343–535

  5. Drive  541.4 mi

    1. Drive from Pittsburgh to Senecacar car 541.4 mi
    10h 17m
    $93–134

  6. Bus, taxi

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    4. Take the taxi from Taqueria Guadalajara - Greenville to Senecataxi taxi
    17h 52m
    $247–365

  7. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Washington Union Stationtrain train Floridian
    2. Take the train from Washington Union Station to Clemson Amtrak Stationtrain train Crescent
    20h 34m
    $464–715

Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP) flights

Calendar39Weekly Planes
Duration3h 28mAverage Duration
Ticket$116Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Seneca.ExpandLaunch map view
  • Distance: 476.6 mi
  • Duration: 4h 50m

What companies run services between Pittsburgh, PA, USA and Seneca, SC, USA?

You can take a train from Pittsburgh Amtrak Station to Seneca via Washington Union Station and Clemson Amtrak Station in around 20h 34m.

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