Rome2Rio

How to get fromPittsburgh to Sikestonby plane, car, bus, taxi, train, or bus (Flixbus)

Find Transport to Sikeston

See all options

There are 10 ways to get from Pittsburgh to Sikeston by plane, car, bus, taxi, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barkley Regional Airport, drive

    best
    1. Fly from Pittsburgh International Airport (PIT) to Barkley Regional Airport (PAH)plane plane PIT - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    8h 40m
    $102–477

  2. Bus, taxi

    1. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    16h 35m
    $201–329

  3. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    19h 6m
    $270–552

  4. Drive 659.2 mi

    1. Drive from Pittsburgh to Sikestoncar car 659.2 mi
    11h 22m
    $121–174

  5. Fly to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    8h 15m
    $224–779

  6. Fly to Williamson County Regional Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Williamson County Regional Airport (MWA)plane plane PIT - MWA
    2. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    8h 58m
    $170–659

  7. Fly to Nashville, bus, drive

    1. Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane plane PIT - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Sikestoncar car
    9h 8m
    $729–1,052

  8. Fly to Cape Girardeau Municipal Airport, taxi

    1. Fly from Pittsburgh International Airport (PIT) to Cape Girardeau Municipal Airport (CGI)plane plane PIT - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    8h 3m
    $172–561

  9. Train, drive (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train
    3. Drive from Fulton Amtrak Station to Sikestoncar car
    20h 2m
    $300–600

  10. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    20h 22m
    $191–373

Pittsburgh International Airport (PIT) to Barkley Regional Airport (PAH) flights

Calendar33Weekly Planes
Duration6h 45mAverage Duration
Ticket$92Cheapest Price
See schedules

Questions & Answers

Map of how to get from Pittsburgh to Sikeston.ExpandLaunch map view
  • Distance: 596.3 mi
  • Duration: 8h 40m

What companies run services between Pittsburgh, PA, USA and Sikeston, MO, USA?

You can take a bus from Pittsburgh Intermodal Station to Sikeston via Chicago, 95th, Sox-35th, Sox-35th Red Line Station, California & 35th Street, Tornado Bus Co - Chicago, and Flying J - Matthews in around 20h 22m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers