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How to get fromPittsburgh to Simpsonvilleby bus, plane, bus (Greyhound), train, taxi, or car

Find Transport to Simpsonville

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There are 6 ways to get from Pittsburgh to Simpsonville by bus, plane, bus (Greyhound), train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Greenville–Spartanburg International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    4h 5m

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Asheville Regional Airport (AVL)plane plane PIT - AVL
    2. Drive from Asheville-Airport-AVL to Simpsonvillecar car
    6h 55m
    $85–461

  3. Bus via Cambridge

    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charlestonbus bus
    3. Take the bus from Charleston to Charlottebus bus
    4. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    16h 26m
    $123–249

  4. Train, bus, taxi

    1. Take the train from Pittsburgh Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte to Servicios Zapata - Spartanburgbus bus
    4. Take the taxi from Servicios Zapata - Spartanburg to Simpsonvilletaxi taxi
    22h 16m
    $518–788

  5. Drive  524.5 mi

    1. Drive from Pittsburgh to Simpsonvillecar car 524.5 mi
    9h 35m
    $96–139

  6. Bus

    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Take the bus from Morgantown Mt Line to Charlestonbus bus
    3. Take the bus from Charleston Bus Station to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    18h 40m
    $145–274

Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP) flights

Calendar54Weekly Planes
Duration3h 33mAverage Duration
Ticket$118Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Simpsonville.ExpandLaunch map view
  • Distance: 439.7 mi
  • Duration: 4h 5m

What companies run services between Pittsburgh, PA, USA and Simpsonville, SC, USA?

You can take a bus from Pittsburgh Intermodal Station to Simpsonville via Cambridge, Charleston, Charlotte, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay O, Tryon St & Dorton St, Charlotte, and Taqueria Guadalajara - Greenville in around 16h 26m.

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