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How to get fromPittsburgh to South Carolinaby bus, plane, train (Amtrak), car, or taxi

Find Transport to South Carolina

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There are 6 ways to get from Pittsburgh to South Carolina by bus, plane, train (Amtrak), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Greenville–Spartanburg International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    3h 57m

  2. Drive 647.3 mi

    cheapest
    1. Drive from Pittsburgh to Charlestoncar car 647.3 mi
    11h 10m
    $119–171

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    18h 54m
    $280–561

  4. Bus, fly to Charlotte Douglas International Airport, taxi

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Charlotte Douglas International Airport (CLT)plane plane PIT - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    4h 16m

  5. Bus, fly to Charleston International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane plane PIT - CHS
    4h 59m

  6. Fly to Myrtle Beach, bus

    1. Fly from Pittsburgh International Airport (PIT) to Myrtle Beach (MYR)plane plane PIT - MYR
    2. Take the bus from Myrtle Beach to Florencebus bus
    6h 30m

Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP) flights

Calendar58Weekly Planes
Duration3h 30mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to South Carolina.ExpandLaunch map view
  • Distance: 439.4 mi
  • Duration: 3h 57m

What companies run services between Pittsburgh, PA, USA and South Carolina, USA?

You can take a train from Pittsburgh Amtrak Station to Charleston via Petersburg Amtrak Station and Charleston Amtrak Station in around 18h 54m.

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