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How to get fromPittsburgh to Southamptonby bus (Greyhound), train (Amtrak), car, bus, plane, train, or bus (Flixbus)

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There are 6 ways to get from Pittsburgh to Southampton by bus (Greyhound), train (Amtrak), car, bus, plane, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Pittsburgh Intermodal Station to King of Prussia Park & Ridebus bus Greyhound US0421
    9h 38m
    $52–91

  2. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to 30th Street Stationtrain train Pennsylvanian
    10h 2m
    $116–233

  3. Drive 303.5 mi

    1. Drive from Pittsburgh to Southamptoncar car 303.5 mi
    5h 15m
    $56–80

  4. Bus to Pittsburgh International Airport, fly, train, line 24 bus

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Philadelphia International Airport (PHL)plane plane PIT - PHL
    3. Take the train from Suburban Station to Fox Chasetrain train
    4. Take the bus from Oxford Av & Loney St to 2nd St Pk & Hampton Av - FSbus bus
    7h 4m

  5. Bus via Reading (Flixbus)

    1. Take the bus from Pittsburgh Intermodal Station to Readingbus bus FlixBus 2642 / ...
    2. Take the bus from Reading to Philadelphia Bus Stationbus bus FlixBus 2650 / ...
    10h 30m
    $60–97

  6. Bus to Penn State University Park Airport, fly

    1. Take the bus from Pittsburgh Intermodal Station to State College Regional Airportbus bus
    2. Fly from Penn State University Park Airport (SCE) to Philadelphia International Airport (PHL)plane plane SCE - PHL
    8h 29m
    $81–415

Pittsburgh to Southampton by bus (Greyhound)

Calendar42Weekly Buses
Duration9h 38mAverage Duration
Ticket$52Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Southampton.ExpandLaunch map view
  • Distance: 322.2 mi
  • Duration: 9h 38m

What companies run services between Pittsburgh, PA, USA and Southampton, PA, USA?

Greyhound USA operates a bus from Pittsburgh Intermodal Station to King of Prussia Park & Ride every 4 hours. Tickets cost $40–85 and the journey takes 6h. Alternatively, Amtrak operates a train from Pittsburgh Amtrak Station to 30th Street Station once daily. Tickets cost $110–230 and the journey takes 7h 29m.

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