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How to get fromPittsburgh to Spartanburgby bus, plane, bus (Greyhound, Flixbus), train, car, or train (Amtrak)

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There are 6 ways to get from Pittsburgh to Spartanburg by bus, plane, bus (Greyhound, Flixbus), train, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Greenville–Spartanburg International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    4h 11m

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Asheville Regional Airport (AVL)plane plane PIT - AVL
    2. Drive from Asheville-Airport-AVL to Spartanburgcar car
    7h 6m
    $81–445

  3. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Spartanburgbus bus
    14h 20m
    $92–179

  4. Bus, train

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the train from Washington Union Station to Spartanburg Stationtrain train Crescent
    15h 56m
    $146–329

  5. Drive  497.1 mi

    1. Drive from Pittsburgh to Spartanburgcar car 497.1 mi
    9h 4m
    $91–131

  6. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Washington Union Stationtrain train Floridian
    2. Take the train from Washington Union Station to Spartanburg Stationtrain train Crescent
    18h 36m
    $182–439

Pittsburgh to Spartanburg by bus and train

Calendar7Weekly Services
Duration15h 56mAverage Duration
Ticket$146Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Spartanburg.ExpandLaunch map view
  • Distance: 446.3 mi
  • Duration: 4h 11m

What companies run services between Pittsburgh, PA, USA and Spartanburg, SC, USA?

You can take a bus from Pittsburgh Intermodal Station to Spartanburg via Cambridge, OH, Cambridge, Charleston, WV, Charlotte Bus Station, and Spartanburg in around 14h 20m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Spartanburg Station via Washington Union Station in around 18h 36m.

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