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How to get fromPittsburgh to Syracuseby bus (Greyhound, Flixbus), train (Amtrak), car, plane, bus (Flixbus), or bus

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There are 7 ways to get from Pittsburgh to Syracuse by bus (Greyhound, Flixbus), train (Amtrak), car, plane, bus (Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Erie

    best
    1. Take the bus from Pittsburgh Intermodal Station to Eriebus bus
    2. Take the bus from Erie to Buffalobus bus
    3. Take the bus from Buffalo to Syracuse Bus Stationbus bus
    9h 5m
    $56–175

  2. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train Floridian
    2. Take the train from Cleveland Amtrak to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    9h 32m
    $144–311

  3. Drive 332.7 mi

    1. Drive from Pittsburgh to Syracusecar car 332.7 mi
    7h 16m
    $61–88

  4. Fly to Syracuse Hancock International Airport

    1. Fly from Pittsburgh International Airport (PIT) to Syracuse Hancock International Airport (SYR)plane plane PIT - SYR
    7h 29m
    $366–803

  5. Bus

    1. Take the bus from Pittsburgh to Buffalobus bus Fab510
    2. Take the bus from Buffalo to Syracuse Bus Stationbus bus Greyhound US0215 / ...
    10h 40m
    $134–283

  6. Bus #2

    1. Take the bus from Pittsburgh to Buffalobus bus Fab510
    2. Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus bus FlixBus 2686 / ...
    12h 12m
    $139–311

  7. Fly to Ithaca Tompkins Regional Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Ithaca Tompkins Regional Airport (ITH)plane plane PIT - ITH
    2. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    9h 27m
    $75–396

Pittsburgh to Syracuse by bus

Calendar14Weekly Buses
Duration9h 5mAverage Duration
Ticket$56Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Syracuse.ExpandLaunch map view
  • Distance: 379 mi
  • Duration: 9h 5m

What companies run services between Pittsburgh, PA, USA and Syracuse, NY, USA?

You can take a bus from Pittsburgh Intermodal Station to Syracuse Bus Station via Erie and Buffalo in around 9h 5m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Syracuse Regional Transportation Center via Cleveland Amtrak in around 9h 32m.

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