There are 8 ways to get from Pittsburgh to Tupelo by plane, car, bus (Greyhound, Flixbus), train, bus, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Golden Triangle Regional Airport, drive
best- Fly from Pittsburgh International Airport (PIT) to Golden Triangle Regional Airport (GTR)plane PIT - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
7h 50m$106–522Bus
- Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
22h 14m$161–262Train, bus via St. Louis
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
24h 51m$249–562Drive 752.6 mi
- Drive from Pittsburgh to Tupelocar 752.6 mi
13h 54m$138–199Fly to Huntsville International Airport-Carl T Jones Field, drive
- Fly from Pittsburgh International Airport (PIT) to Huntsville International Airport-Carl T Jones Field (HSV)plane PIT - HSV
- Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar
8h 47m$156–764Fly to Memphis, bus
- Fly from Pittsburgh International Airport (PIT) to Memphis (MEM)plane PIT - MEM
- Take the bus from Memphis Bus Station to Tupelobus
9h 50m$192–950Train, bus
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
23h 19m$224–457Bus via Auburn Gresham
- Take the bus from Pittsburgh Intermodal Station to Chicagobus
- Take the bus from Chicago to Champaign Intermodal Trans Ctrbus
- Take the bus from Champaign Intermodal Trans Ctr to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
26h 29m$193–295
Pittsburgh International Airport (PIT) to Golden Triangle Regional Airport (GTR) flights
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Tupelo is to drive which costs $130 - $200 and takes 13h 54m.
The fastest way to get from Pittsburgh to Tupelo is to fly and drive which takes 7h 50m and costs $100 - $550.
No, there is no direct bus from Pittsburgh station to Tupelo. However, there are services departing from Pittsburgh Intermodal Station and arriving at Tupelo via St Louis Bus Station and Memphis Bus Station. The journey, including transfers, takes approximately 22h 14m.
The distance between Pittsburgh and Tupelo is 761 miles. The road distance is 757 miles.
The best way to get from Pittsburgh to Tupelo without a car is to bus which takes 22h 14m and costs $160 - $270.
It takes approximately 7h 50m to get from Pittsburgh to Tupelo, including transfers.
Pittsburgh to Tupelo bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Tupelo bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Tupelo is 1h behind Pittsburgh. It is currently 1:27 AM in Pittsburgh and 12:27 AM in Tupelo.
Yes, the driving distance between Pittsburgh to Tupelo is 757 miles. It takes approximately 13h 54m to drive from Pittsburgh to Tupelo.
What companies run services between Pittsburgh, PA, USA and Tupelo, MS, USA?
You can take a bus from Pittsburgh Intermodal Station to Tupelo via St Louis Bus Station, Memphis Bus Station, and Tupelo in around 22h 14m.
- Website
- delta.com
Flights from Pittsburgh International Airport to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $95–550
Flights from Pittsburgh International Airport to Huntsville International Airport-Carl T Jones Field via Detroit
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $140–800
Flights from Pittsburgh International Airport to Huntsville International Airport-Carl T Jones Field via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $130–750
Flights from Pittsburgh International Airport to Huntsville International Airport-Carl T Jones Field via New York La Guardia
- Ave. Duration
- 6h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–950
Flights from Pittsburgh International Airport to Memphis via Detroit
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Pittsburgh International Airport to Memphis via Atlanta
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $190–1,000
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $65–170
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to St Louis Bus Station
- Ave. Duration
- 12h 55m
- Frequency
- 3 times a day
- Estimated price
- $95–150
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Chicago Bus Station to Memphis Bus Station
- Ave. Duration
- 9h 35m
- Frequency
- Once daily
- Estimated price
- $85–140
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Book your Pittsburgh to Tupelo bus tickets online with Omio.
There are 35+ hotels available in Tupelo.





