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How to get fromPittsburgh to West Lafayetteby bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), bus, or train

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There are 8 ways to get from Pittsburgh to West Lafayette by bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Pittsburgh Intermodal Station to Lafayette Bus Stopbus bus FlixBus N2642 / ...
    8h 40m
    $65–120

  2. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train Cardinal
    13h 47m
    $190–391

  3. Drive 418.4 mi

    1. Drive from Pittsburgh to West Lafayettecar car 418.4 mi
    7h 16m
    $77–111

  4. Fly to Purdue University Airport

    1. Fly from Pittsburgh International Airport (PIT) to Purdue University Airport (LAF)plane plane PIT - LAF
    6h 20m
    $76–403

  5. Bus via Indianapolis

    1. Take the bus from Pittsburgh Intermodal Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Lafayette Bus Stopbus bus Greyhound US0100 / ...
    10h 10m
    $68–129

  6. Fly to Indianapolis, bus

    1. Fly from Pittsburgh International Airport (PIT) to Indianapolis (IND)plane plane PIT - IND
    2. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    7h 45m
    $123–579

  7. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    2. Take the bus from Chicago Bus Station to Lafayette Bus Stopbus bus
    7h 47m
    $407–1,177

  8. Fly to Chicago Midway International Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    8h 30m
    $102–442

Pittsburgh to West Lafayette by bus

Calendar16Weekly Buses
Duration8h 40mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to West Lafayette.ExpandLaunch map view
  • Distance: 420.6 mi
  • Duration: 8h 40m

What companies run services between Pittsburgh, PA, USA and West Lafayette, IN, USA?

Flixbus USA operates a bus from Pittsburgh Intermodal Station to Lafayette Bus Stop once daily. Tickets cost $65–120 and the journey takes 8h 40m. FlixBus-us also services this route once daily. Alternatively, you can take a train from Pittsburgh Amtrak Station to Lafayette Amtrak Station via Chicago Union Station in around 13h 47m.

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