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How to get fromPittsburgh to Winston-Salemby plane, bus (Greyhound), train, bus, or car

Find Transport to Winston-Salem

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There are 7 ways to get from Pittsburgh to Winston-Salem by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Pittsburgh International Airport (PIT) to Piedmont Triad International Airport (GSO)plane plane PIT - GSO
    6h 59m
    $91–453

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Take the bus from Morgantown Mt Line to Charlestonbus bus
    3. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    12h 10m
    $58–150

  3. Bus via Cambridge

    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charlestonbus bus
    3. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    11h 40m
    $73–144

  4. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    18h 24m
    $372–579

  5. Drive  389.2 mi

    1. Drive from Pittsburgh to Winston-Salemcar car 389.2 mi
    6h 55m
    $69–100

  6. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Charlotte Douglas International Airport (CLT)plane plane PIT - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 58m
    $127–701

  7. Fly to Raleigh-Durham International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Raleigh-Durham International Airport (RDU)plane plane PIT - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    7h 49m
    $109–590

Pittsburgh to Winston-Salem by bus

Calendar7Weekly Buses
Duration11h 40mAverage Duration
Ticket$73Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Winston-Salem.ExpandLaunch map view
  • Distance: 352.3 mi
  • Duration: 6h 59m

What companies run services between Pittsburgh, PA, USA and Winston-Salem, NC, USA?

United Airlines, American Airlines, and two other airlines fly from Pittsburgh International Airport (PIT) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Winston Salem(Trans Center) via Cambridge, Charleston, and Charleston Bus Station in around 11h 40m.

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