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How to get fromPittsburgh to Wiseby plane, car, bus, or train

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There are 7 ways to get from Pittsburgh to Wise by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tri-Cities Regional Tn/Va Airport, drive

    best
    1. Fly from Pittsburgh International Airport (PIT) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane PIT - TRI
    2. Drive from Tri-Cities-Regional-Airport-TRI to Wisecar car
    7h 31m
    $98–508

  2. Drive 379.5 mi

    cheapest
    1. Drive from Pittsburgh to Wisecar car 379.5 mi
    7h 4m
    $70–100

  3. Bus, drive

    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Wythevillebus bus
    4. Take the bus from Wytheville Rural King Parking Lot to Bristol Exit 5 Park & Ride Lotbus bus
    5. Drive from Bristol Exit 5 Park & Ride Lot to Wisecar car
    12h 54m
    $93–193

  4. Train, bus, drive via Roanoke

    1. Take the train from Pittsburgh Amtrak Station to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Roanoketrain train
    3. Take the bus from Roanoke Amtrak Station to Exit 118 - Park and Ridebus bus Swb
    4. Take the bus from Christiansburg to Bristol Exit 5 Park & Ride Lotbus bus
    5. Drive from Bristol Exit 5 Park & Ride Lot to Wisecar car
    20h 31m
    $202–389

  5. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Wisecar car
    7h 56m
    $128–613

  6. Bus, drive via Washington

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Bristol Exit 5 Park & Ride Lotbus bus
    3. Drive from Bristol Exit 5 Park & Ride Lot to Wisecar car
    15h 31m
    $97–149

  7. Train, bus, drive

    1. Take the train from Pittsburgh Amtrak Station to Washington Union Stationtrain train
    2. Take the bus from Washington Union Station to Bristol Exit 5 Park & Ride Lotbus bus
    3. Drive from Bristol Exit 5 Park & Ride Lot to Wisecar car
    18h 11m
    $156–270

Pittsburgh International Airport (PIT) to Tri-Cities Regional Tn/Va Airport (TRI) flights

Calendar59Weekly Planes
Duration4h 52mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Wise.ExpandLaunch map view
  • Distance: 380.7 mi
  • Duration: 7h 31m

What companies run services between Pittsburgh, PA, USA and Wise, VA, USA?

There is no direct connection from Pittsburgh to Wise. However, you can take the bus to Pittsburgh International Airport, walk to Pittsburgh-Airport-PIT airport, fly to Tri-Cities Regional Tn/Va Airport (TRI), then drive to Wise. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Wise via Cambridge, OH, Cambridge, Charleston, WV, Wytheville, Wytheville Rural King Parking Lot, and Bristol Exit 5 Park & Ride Lot in around 12h 54m.

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