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How to get fromPittsburgh to Wythevilleby bus (Greyhound), train, bus, car, plane, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Pittsburgh to Wytheville by bus (Greyhound), train, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Cambridge

    best
    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Wythevillebus bus
    9h 24m
    $66–160

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Take the bus from Morgantown to Charlestonbus bus
    3. Take the bus from Charleston, WV to Wythevillebus bus
    9h 59m
    $54–163

  3. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Washington Union Stationtrain train Floridian
    2. Take the bus from Washington Union Station to Wytheville Rural King Parking Lotbus bus Highlands Rhythm
    15h 40m
    $140–246

  4. Drive 306.6 mi

    1. Drive from Pittsburgh to Wythevillecar car 306.6 mi
    5h 24m
    $56–81

  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Charlotte Douglas International Airport (CLT)plane plane PIT - CLT
    2. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    7h 45m
    $153–636

  6. Bus via Washington

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the bus from DC Union Station to Rural King Shopping Centerbus bus Virginia Breeze
    12h 35m
    $78–142

  7. Fly to Roanoke Regional Airport-Woodrum Field, bus

    1. Fly from Pittsburgh International Airport (PIT) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane PIT - ROA
    2. Take the bus from Airport to Exit 118 - Park and Ridebus bus
    3. Take the bus from Route 460 Park and Ride to Rural King Shopping Centerbus bus
    9h 32m
    $77–401

Pittsburgh to Wytheville by train and bus

Calendar7Weekly Services
Duration15h 40mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Wytheville.ExpandLaunch map view
  • Distance: 385.6 mi
  • Duration: 9h 24m

What companies run services between Pittsburgh, PA, USA and Wytheville, VA, USA?

You can take a bus from Pittsburgh Intermodal Station to Wytheville via Cambridge, OH, Cambridge, Charleston, WV, and Wytheville in around 9h 24m.

Airlines
Train operators
Bus operators

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