Rome2Rio

How to get fromPittsburgh to Wythevilleby bus (Greyhound), train, bus, car, plane, or bus (Greyhound, Flixbus)

Find Transport to Wytheville

See all options

There are 7 ways to get from Pittsburgh to Wytheville by bus (Greyhound), train, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Cambridge

    best
    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus bus
    2. Take the bus from Cambridge to Charlestonbus bus
    3. Take the bus from Charleston to Wythevillebus bus
    9h 29m
    $68–156

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Take the bus from Morgantown Mt Line to Charlestonbus bus
    3. Take the bus from Charleston to Wythevillebus bus
    9h 59m
    $54–163

  3. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Washington Union Stationtrain train Floridian
    2. Take the bus from Washington Union Station to Wytheville Rural King Parking Lotbus bus Highlands Rhythm
    15h 40m
    $205–306

  4. Drive  306.6 mi

    1. Drive from Pittsburgh to Wythevillecar car 306.6 mi
    5h 24m
    $56–81

  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Charlotte Douglas International Airport (CLT)plane plane PIT - CLT
    2. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    7h 48m
    $169–758

  6. Bus via Washington

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Washington Union Station to Wytheville Rural King Parking Lotbus bus Highlands Rhythm
    13h
    $83–124

  7. Fly to Roanoke Regional Airport-Woodrum Field, bus

    1. Fly from Pittsburgh International Airport (PIT) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane PIT - ROA
    2. Take the bus from Airport to Exit 118 - Park and Ridebus bus
    3. Take the bus from Christiansburg to Wytheville Rural King Parking Lotbus bus
    9h 45m
    $90–450

Pittsburgh to Wytheville by train and bus

Calendar7Weekly Services
Duration15h 40mAverage Duration
Ticket$205Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Pittsburgh to Wytheville.ExpandLaunch map view
  • Distance: 387.3 mi
  • Duration: 9h 29m

What companies run services between Pittsburgh, PA, USA and Wytheville, VA, USA?

You can take a bus from Pittsburgh Intermodal Station to Wytheville via Cambridge, Charleston, and Wytheville in around 9h 29m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There