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How to get fromPlymouth to Buffaloby bus, plane, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

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There are 8 ways to get from Plymouth to Buffalo by bus, plane, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from Park & Ride Lot, Ex 13 Info. Ctr. to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    4h 45m
    $102–555

  2. Bus

    cheapest
    1. Take the bus from Park & Ride Lot, Ex 13 Info. Ctr. to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    12h
    $89–164

  3. Train

    1. Take the train from Kingston to South Stationtrain train Kingston Line
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    15h 2m
    $159–482

  4. Drive 486 mi

    1. Drive from Plymouth to Buffalocar car 486 mi
    8h 27m
    $89–129

  5. Drive to Provincetown Municipal Airport, fly to Buffalo Niagara International Airport

    1. Drive from Plymouth to Provincetown Municipal Airport (PVC)car car
    2. Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane plane PVC - BUF
    7h 13m
    $116–650

  6. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Park & Ride Lot, Ex 13 Info. Ctr. to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 59m
    $134–620

  7. Fly Barnstable Municipal Airport to Buffalo Niagara International Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane plane HYA - BUF
    7h 40m
    $117–654

  8. Bus via Ithaca

    1. Take the bus from Park & Ride Lot, Ex 13 Info. Ctr. to Boston South Busesbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    14h 24m
    $107–224

Plymouth to Buffalo by bus

Calendar14Weekly Buses
Duration12hAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

Map of how to get from Plymouth to Buffalo.ExpandLaunch map view
  • Distance: 453.3 mi
  • Duration: 4h 45m

What companies run services between Plymouth, MA, USA and Buffalo, NY, USA?

You can take a bus from Park & Ride Lot, Ex 13 Info. Ctr. to Buffalo via Boston, South Station and Boston in around 12h. Alternatively, you can take a train from Kingston to Buffalo via South Station, Boston, and Buffalo Depew Station in around 15h 2m.

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