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How to get fromPlymouth Meeting to Chicagoby bus, train, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus (Greyhound)

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There are 10 ways to get from Plymouth Meeting to Chicago by bus, train, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 51 bus, train to Philadelphia International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Germantown Pk & Marple Ln to Germantown Av & Bethlehem Pk - FSbus bus
    2. Take the train from Chestnut Hill West to Gray 30th St Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    5h 47m
    $151–384

  2. Bus to Lehigh Valley International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Doylestown SEPTA Station to Lehigh Valley International Airportbus bus
    2. Fly from Lehigh Valley International Airport (ABE) to Chicago O'Hare International Airport (ORD)plane plane ABE - ORD
    8h 29m
    $68–332

  3. Bus

    1. Take the bus from King of Prussia Park & Ride to Harrisburg Bus Stationbus bus Greyhound US0421
    2. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640 / ...
    21h 12m
    $139–241

  4. Train via Washington (Amtrak)

    1. Take the train from 30th Street Station to Washington Union Stationtrain train Northeast Regional / ...
    2. Take the train from Washington Union Station to Chicago Union Stationtrain train Floridian / ...
    22h 29m
    $276–1,206

  5. Drive 747.1 mi

    1. Drive from Plymouth Meeting to Chicagocar car 747.1 mi
    12h 11m
    $137–197

  6. Line 51 bus, train to Philadelphia International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Germantown Pk & Marple Ln to Germantown Av & Bethlehem Pk - FSbus bus
    2. Take the train from Chestnut Hill West to Gray 30th St Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Chicago O'Hare International Airport (ORD)plane plane PHL - ORD
    6h 16m
    $131–234

  7. Train to Baltimore-Washington International Airport, fly to Chicago Midway International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Chicago Midway International Airport (MDW)plane plane BWI - MDW
    7h 1m
    $152–961

  8. Fly Philadelphia International Airport to General Mitchell International Airport, train

    1. Fly from Philadelphia International Airport (PHL) to General Mitchell International Airport (MKE)plane plane PHL - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    8h 25m
    $188–883

  9. Bus via Baltimore (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Baltimore Greyhound Garagebus bus Greyhound US0305
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    27h 14m
    $142–276

  10. Train (Amtrak)

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    29h 35m
    $336–706

Plymouth Meeting to Chicago by bus

Calendar7Weekly Buses
Duration21h 12mAverage Duration
Ticket$139Cheapest Price
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Questions & Answers

Map of how to get from Plymouth Meeting to Chicago.ExpandLaunch map view
  • Distance: 700.2 mi
  • Duration: 5h 47m

What companies run services between Plymouth Meeting, PA, USA and Chicago, IL, USA?

You can take a bus from Chemical Rd & Germantown Pk - MBFS to Chicago Bus Station via Gulph Mills Station - onsite, South Gulph Rd & Bill Smith Blvd, King of Prussia Park & Ride, and Harrisburg Bus Station in around 21h 12m. Alternatively, you can take a bus from Germantown Pk & Marple Ln to Chicago Union Station via Germantown Av & Bethlehem Pk - FS, Chestnut Hill West, 30th Street Station, and Washington Union Station in around 22h 29m.

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