There are 8 ways to get from Plymouth to Chicago by plane, train (Amtrak), bus (Amtrak), car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Detroit to Chicago Midway International Airport
best- Fly from Detroit (DTW) to Chicago Midway International Airport (MDW)plane DTW - MDW
2h 15m$194–538Drive 256.4 mi
cheapest- Drive from Plymouth to Chicagocar 256.4 mi
4h 19m$47–68Train (Amtrak)
- Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain Wolverine
4h 42m$132–227Bus (Amtrak)
- Take the bus from Ann Arbor Amtrak Station to Chicago Union Stationbus Amtrak Thruway Connecting Service
5h 3m$137–187Fly Detroit to Chicago O'Hare International Airport
- Fly from Detroit (DTW) to Chicago O'Hare International Airport (ORD)plane DTW - ORD
2h 35m$204–728Drive to Capital Region International Airport, fly to Chicago O'Hare International Airport
- Drive from Plymouth to Lansing-Airport-LANcar
- Fly from Capital Region International Airport (LAN) to Chicago O'Hare International Airport (ORD)plane LAN - ORD
3h 20m$56–335Drive to Bishop International Airport, fly to Chicago O'Hare International Airport
- Drive from Plymouth to Bishop International Airport (FNT)car
- Fly from Bishop International Airport (FNT) to Chicago O'Hare International Airport (ORD)plane FNT - ORD
3h 22m$47–259Bus via Chicago Bus Station
- Take the bus from Ann Arbor to Chicago Bus Stationbus Greyhound US0160
5h 24m$92–137
Detroit (DTW) to Chicago Midway International Airport (MDW) flights
Questions & Answers
The cheapest way to get from Plymouth to Chicago is to drive which costs $45 - $70 and takes 4h 19m.
The fastest way to get from Plymouth to Chicago is to fly which takes 2h 15m and costs $190 - $550.
No, there is no direct bus from Plymouth station to Chicago station. However, there are services departing from Ann Arbor Amtrak Station and arriving at Chicago Union Station via . The journey, including transfers, takes approximately 5h 3m.
No, there is no direct train from Plymouth station to Chicago station. However, there are services departing from Ann Arbor Amtrak Station and arriving at Chicago Union Station via . The journey, including transfers, takes approximately 4h 42m.
The distance between Plymouth and Chicago is 257 miles. The road distance is 257.8 miles.
The best way to get from Plymouth to Chicago without a car is to train which takes 4h 42m and costs $130 - $230.
It takes approximately 2h 15m to get from Plymouth to Chicago, including transfers.
Plymouth to Chicago bus services, operated by Amtrak, depart from Ann Arbor Amtrak Station.
Plymouth to Chicago train services, operated by Amtrak, depart from Ann Arbor Amtrak Station.
The best way to get from Plymouth to Chicago is to fly which takes 2h 15m and costs $190 - $550. Alternatively, you can train, which costs $130 - $230 and takes 4h 42m, you could also bus, which costs $130 - $190 and takes 5h 3m.
What companies run services between Plymouth, Wayne County, MI, USA and Chicago, IL, USA?
Delta and Southwest Airlines fly from Detroit (DTW) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, Amtrak operates a train from Ann Arbor Amtrak Station to Chicago Union Station 3 times a day. Tickets cost $75–160 and the journey takes 4h 18m.
- Website
- aa.com
Flights from Detroit to Chicago O'Hare International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $40–310
Flights from Capital Region International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $40–310
Flights from Bishop International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $35–240
- Website
- delta.com
Flights from Detroit to Chicago Midway International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $50–360
Flights from Detroit to Chicago O'Hare International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $40–310
Flights from Capital Region International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 3h 19m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $50–330
- Website
- united.com
Flights from Detroit to Chicago O'Hare International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $40–310
Flights from Capital Region International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $40–310
Flights from Bishop International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $35–240
- Website
- southwest.com
Flights from Detroit to Chicago Midway International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $50–360
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ann Arbor Amtrak Station to Chicago Union Station
- Ave. Duration
- 4h 18m
- Frequency
- 3 times a day
- Estimated price
- $75–160
- Website
- Amtrak
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Ann Arbor Amtrak Station to Chicago Union Station
- Ave. Duration
- 4h 39m
- Frequency
- Once a week
- Estimated price
- $80–120
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Ann Arbor to Chicago Bus Station
- Ave. Duration
- 5h
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Ann Arbor to Chicago Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 5 times a week
- Estimated price
- $35–65
- Schedules at
- Flixbus USA
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More Questions & Answers
Plymouth to Chicago bus services, operated by Amtrak, arrive at Chicago Union Station.
Chicago is 1h behind Plymouth. It is currently 2:08 AM in Plymouth and 1:08 AM in Chicago.
Plymouth to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Plymouth to Chicago is 258 miles. It takes approximately 4h 19m to drive from Plymouth to Chicago.
There are 1080+ hotels available in Chicago.






