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How to get fromPontiac to Knoxvilleby train, plane, bus (Amtrak, Flixbus), bus, car, or bus (Greyhound)

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There are 8 ways to get from Pontiac to Knoxville by train, plane, bus (Amtrak, Flixbus), bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Detroit, fly to Mcghee Tyson Airport

    best
    1. Take the train from Pontiac Amtrak Station to Dearborntrain train
    2. Fly from Detroit (DTW) to Mcghee Tyson Airport (TYS)plane plane DTW - TYS
    4h 46m
    $216–1,041

  2. Drive  525.8 mi

    cheapest
    1. Drive from Pontiac to Knoxvillecar car 525.8 mi
    9h 4m
    $96–139

  3. Bus via Toledo

    1. Take the bus from Detroit to Toledobus bus
    2. Take the bus from Toledo Bus Stop to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    29h 41m
    $297–441

  4. Bus, train

    1. Take the bus from Detroit to Toledobus bus
    2. Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    32h 33m
    $351–632

  5. Drive to Capital Region International Airport, fly to Mcghee Tyson Airport

    1. Drive from Pontiac to Lansing-Airport-LANcar car
    2. Fly from Capital Region International Airport (LAN) to Mcghee Tyson Airport (TYS)plane plane LAN - TYS
    6h 27m
    $239–1,190

  6. Train to Detroit, fly to Chattanooga Metropolitan Airport, drive

    1. Take the train from Pontiac Amtrak Station to Dearborntrain train
    2. Fly from Detroit (DTW) to Chattanooga Metropolitan Airport (CHA)plane plane DTW - CHA
    3. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    6h 25m
    $109–519

  7. Bus, train via Farragut

    1. Take the bus from Detroit to Toledobus bus
    2. Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    32h 44m
    $392–711

  8. Bus

    1. Take the bus from Downtown Pontiac to Larned & Griswoldbus bus 462
    2. Take the bus from Detroit Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    33h 17m
    $295–465

Detroit (DTW) to Mcghee Tyson Airport (TYS) flights

Calendar48Weekly Planes
Duration3h 13mAverage Duration
Ticket$154Cheapest Price
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Questions & Answers

Map of how to get from Pontiac to Knoxville.ExpandLaunch map view
  • Distance: 500.9 mi
  • Duration: 4h 46m

What companies run services between Pontiac, MI, USA and Knoxville, TN, USA?

You can take a bus from Downtown Pontiac to Knoxville via Woodward & Baltimore, Detroit, Toledo Bus Stop, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 29h 41m.

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