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How to get fromPoplar Bluff to Biloxiby car, bus, train, or plane

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There are 7 ways to get from Poplar Bluff to Biloxi by car, bus, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus

    best
    1. Drive from Poplar Bluff to Cape Girardeaucar car
    2. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    3. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    18h 40m
    $127–203

  2. Drive  509.7 mi

    cheapest
    1. Drive from Poplar Bluff to Biloxicar car 509.7 mi
    9h 5m
    $88–126

  3. Train to Lambert–St. Louis International Airport, fly to Gulfport-Biloxi Regional Airport

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Gulfport-Biloxi Regional Airport (GPT)plane plane STL - GPT
    11h 28m
    $218–666

  4. Train, bus

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    24h 54m
    $250–398

  5. Drive to Mc Kellar-Sipes Regional Airport, fly to Gulfport-Biloxi Regional Airport

    1. Drive from Poplar Bluff to Mc Kellar-Sipes Regional Airport (MKL)car car
    2. Fly from Mc Kellar-Sipes Regional Airport (MKL) to Gulfport-Biloxi Regional Airport (GPT)plane plane MKL - GPT
    8h 9m
    $123–468

  6. Drive to Cape Girardeau Municipal Airport, fly to Gulfport-Biloxi Regional Airport

    1. Drive from Poplar Bluff to Cape Girardeau Municipal Airport (CGI)car car
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Gulfport-Biloxi Regional Airport (GPT)plane plane CGI - GPT
    9h 36m
    $147–562

  7. Train to Lambert–St. Louis International Airport, fly to Louis Armstrong New Orleans International Airport, train

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY)plane plane STL - MSY
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    11h 57m
    $236–816

Poplar Bluff to Biloxi by train and bus

Calendar7Weekly Services
Duration24h 54mAverage Duration
Ticket$250Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poplar Bluff to Biloxi.ExpandLaunch map view
  • Distance: 754.9 mi
  • Duration: 18h 40m

What companies run services between Poplar Bluff, MO, USA and Biloxi, MS, USA?

There is no direct connection from Poplar Bluff to Biloxi. However, you can drive to Cape Girardeau, take the bus to New Orleans Bus Station, then take the bus to Biloxi Transit Center. Alternatively, you can drive from Poplar Bluff to Biloxi in around 9h 5m.

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