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How to get fromPoplar Bluff to Buffaloby car, plane, bus, train (Amtrak), or train

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There are 6 ways to get from Poplar Bluff to Buffalo by car, plane, bus, train (Amtrak), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Barkley Regional Airport, fly

    best
    1. Drive from Poplar Bluff to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Buffalo Niagara International Airport (BUF)plane plane PAH - BUF
    9h 37m
    $140–680

  2. Drive, bus

    cheapest
    1. Drive from Poplar Bluff to Cape Girardeaucar car
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Columbusbus bus
    4. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    23h 35m
    $124–249

  3. Train (Amtrak)

    1. Take the train from Poplar Bluff Station to Chicago Union Stationtrain train Texas Eagle
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    23h 44m
    $261–711

  4. Drive  850.6 mi

    1. Drive from Poplar Bluff to Buffalocar car 850.6 mi
    14h 33m
    $156–225

  5. Train to Lambert–St. Louis International Airport, fly

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)plane plane STL - BUF
    11h 4m
    $168–802

  6. Train, bus

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    29h 11m
    $174–456

Poplar Bluff to Buffalo by train (Amtrak)

Calendar10Weekly Trains
Duration23h 44mAverage Duration
Ticket$261Cheapest Price
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Questions & Answers

Map of how to get from Poplar Bluff to Buffalo.ExpandLaunch map view
  • Distance: 779 mi
  • Duration: 9h 37m

What companies run services between Poplar Bluff, MO, USA and Buffalo, NY, USA?

You can take a train from Poplar Bluff Station to Buffalo via Chicago Union Station and Buffalo Depew Station in around 23h 44m.

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Bus operators

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