Rome2Rio

How to get fromPoplar Bluff to Destinby train, plane, car, bus, or taxi

Find Transport to Destin

See all options

There are 9 ways to get from Poplar Bluff to Destin by train, plane, car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Lambert–St. Louis International Airport, fly to Destin–Fort Walton Beach Airport

    best
    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    8h 35m
    $182–634

  2. Drive 612.2 mi

    cheapest
    1. Drive from Poplar Bluff to Destincar car 612.2 mi
    11h 31m
    $112–162

  3. Drive, bus, taxi

    1. Drive from Poplar Bluff to Cape Girardeaucar car
    2. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    3. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    4. Take the bus from Biloxi to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    23h 45m
    $251–390

  4. Train, bus, taxi via Carbondale

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    5. Take the bus from Gulfport to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    29h 16m
    $424–786

  5. Drive to Cape Girardeau Municipal Airport, fly to Pensacola International Airport, taxi

    1. Drive from Poplar Bluff to Cape Girardeau Municipal Airport (CGI)car car
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Pensacola International Airport (PNS)plane plane CGI - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    4h 35m
    $253–648

  6. Train to Midamerica St. Louis Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    9h 1m
    $185–552

  7. Train to Lambert–St. Louis International Airport, fly to Northwest Florida Beaches International Airport, taxi

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    3. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    9h 19m
    $287–769

  8. Train to Lambert–St. Louis International Airport, fly to Pensacola International Airport, taxi

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS)plane plane STL - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    9h 27m
    $257–699

  9. Train, bus, taxi

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    29h 13m
    $320–536

Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar25Weekly Planes
Duration3h 14mAverage Duration
Ticket$88Cheapest Price
See schedules

Questions & Answers

Map of how to get from Poplar Bluff to Destin.ExpandLaunch map view
  • Distance: 802.6 mi
  • Duration: 8h 35m

What companies run services between Poplar Bluff, MO, USA and Destin, FL, USA?

There is no direct connection from Poplar Bluff to Destin. However, you can take the train to St. Louis, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Destin–Fort Walton Beach Airport (VPS), then take the taxi to Destin. Alternatively, you can drive to Cape Girardeau, take the bus to New Orleans Bus Station, take the bus to Biloxi Transit Center, walk to Biloxi, take the bus to Crestview, then take the taxi to Destin.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound