There are 7 ways to get from Poplar Bluff to Greenville by car, plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Jonesboro Municipal Airport, fly to Greenville–Spartanburg International Airport
best- Drive from Poplar Bluff to Jonesboro Municipal Airport (JBR)car
- Fly from Jonesboro Municipal Airport (JBR) to Greenville–Spartanburg International Airport (GSP)plane JBR - GSP
5h 54m$139–616Drive 582.6 mi
cheapest- Drive from Poplar Bluff to Greenvillecar 582.6 mi
10h 15m$107–154Drive, bus
- Drive from Poplar Bluff to Cape Girardeaucar
- Take the bus from Cape Girardeau to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
18h 59m$161–359Drive to Mc Kellar-Sipes Regional Airport, fly to Greenville–Spartanburg International Airport
- Drive from Poplar Bluff to Mc Kellar-Sipes Regional Airport (MKL)car
- Fly from Mc Kellar-Sipes Regional Airport (MKL) to Greenville–Spartanburg International Airport (GSP)plane MKL - GSP
6h 52m$200–781Train to Lambert–St. Louis International Airport, fly to Charlotte Douglas International Airport, bus
- Take the train from Poplar Bluff Station to St. Louistrain
- Fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT)plane STL - CLT
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus
13h 11m$234–975Train, bus via Carbondale
- Take the train from Poplar Bluff Station to St. Louistrain
- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus
- Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
21h 51m$200–444Train, bus
- Take the train from Poplar Bluff Station to St. Louistrain
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
22h 36m$200–439
Jonesboro Municipal Airport (JBR) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Poplar Bluff to Greenville is to drive which costs $100 - $160 and takes 10h 15m.
The fastest way to get from Poplar Bluff to Greenville is to drive and fly which takes 5h 54m and costs $130 - $650.
The distance between Poplar Bluff and Greenville is 573 miles. The road distance is 586 miles.
The best way to get from Poplar Bluff to Greenville without a car is to train and bus via Carbondale which takes 21h 51m and costs $200 - $450.
It takes approximately 5h 54m to get from Poplar Bluff to Greenville, including transfers.
Greenville is 1h ahead of Poplar Bluff. It is currently 1:48 AM in Poplar Bluff and 2:48 AM in Greenville.
Yes, the driving distance between Poplar Bluff to Greenville is 586 miles. It takes approximately 10h 15m to drive from Poplar Bluff to Greenville.
There are 230+ hotels available in Greenville.
What companies run services between Poplar Bluff, MO, USA and Greenville, SC, USA?
There is no direct connection from Poplar Bluff to Greenville. However, you can drive to Jonesboro Municipal Airport (JBR) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Greenville. Alternatively, you can take a vehicle from Poplar Bluff to Greenville via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 18h 59m.
- Website
- aa.com
Flights from Jonesboro Municipal Airport to Greenville–Spartanburg International Airport via Nashville, Charlotte Douglas International Airport
- Ave. Duration
- 7h 21m
- When
- Sunday and Thursday
- Estimated price
- $100–550
Flights from Mc Kellar-Sipes Regional Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 5h 28m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–700
Flights from Mc Kellar-Sipes Regional Airport to Greenville–Spartanburg International Airport via Atlanta, Charlotte Douglas International Airport
- Ave. Duration
- 7h 47m
- When
- Monday, Tuesday, Thursday, Friday, and Saturday
- Estimated price
- $280–1,000
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $120–700
- Website
- southwest.com
Flights from Jonesboro Municipal Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $90–550
Flights from Mc Kellar-Sipes Regional Airport to Greenville–Spartanburg International Airport via Atlanta, Nashville
- Ave. Duration
- 5h 55m
- When
- Saturday
- Estimated price
- $310–1,200
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Tuesday and Wednesday
- Estimated price
- $130–700
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport via Chicago Midway
- Ave. Duration
- 4h 18m
- When
- Monday to Wednesday
- Estimated price
- $160–800
- Website
- delta.com
Flights from Jonesboro Municipal Airport to Greenville–Spartanburg International Airport via Nashville, Atlanta
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $290–750
Flights from Mc Kellar-Sipes Regional Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 41m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $250–800
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Poplar Bluff Station to St. Louis
- Ave. Duration
- 4h 41m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- Amtrak
Train from Poplar Bluff Station to St. Louis
- Ave. Duration
- 4h 41m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- Amtrak
Train from Poplar Bluff Station to St. Louis
- Ave. Duration
- 4h 41m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to Memphis Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $27–55
- Website
- Greyhound
Bus from Memphis Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- 4 times a day
- Estimated price
- $55–110
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Twice daily
- Estimated price
- $85–160
- Website
- Greyhound
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $45–150
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $45–150
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $45–150
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $15–26
- Schedules at
- Flixbus USA
Bus from Carbondale Intermodal Station to Atlanta Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $90–150
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Amtrak
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide











