Rome2Rio

How to get fromPoplar Bluff to Key Westby train, plane, car, bus, or ferry

Find Transport to Key West

See all options

There are 8 ways to get from Poplar Bluff to Key West by train, plane, car, bus, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Lambert–St. Louis International Airport, fly

    best
    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane plane STL - EYW
    10h 55m
    $178–622

  2. Drive to Mc Kellar-Sipes Regional Airport, fly

    cheapest
    1. Drive from Poplar Bluff to Mc Kellar-Sipes Regional Airport (MKL)car car
    2. Fly from Mc Kellar-Sipes Regional Airport (MKL) to Key West International Airport (EYW)plane plane MKL - EYW
    6h 58m
    $106–409

  3. Drive, bus

    1. Drive from Poplar Bluff to Cape Girardeaucar car
    2. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    6. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    34h 52m
    $216–428

  4. Drive 1,231.4 mi

    1. Drive from Poplar Bluff to Key Westcar car 1,231.4 mi
    23h 40m
    $225–325

  5. Train to Midamerica St. Louis Airport, fly

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Midamerica St. Louis Airport (BLV) to Key West International Airport (EYW)plane plane BLV - EYW
    19h 7m
    $171–530

  6. Drive to Cape Girardeau Municipal Airport, fly

    1. Drive from Poplar Bluff to Cape Girardeau Municipal Airport (CGI)car car
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Key West International Airport (EYW)plane plane CGI - EYW
    25h 36m
    $109–421

  7. Train, bus

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    38h 47m
    $260–520

  8. Train, bus, ferry

    1. Take the train from Poplar Bluff Station to Longviewtrain train
    2. Take the bus from Longview Bus Station to Houston Bus Stationbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    42h 7m
    $517–745

Poplar Bluff to Key West by train, bus, and foot

Calendar10Weekly Services
Duration38h 47mAverage Duration
Ticket$260Cheapest Price
See schedules

Questions & Answers

Map of how to get from Poplar Bluff to Key West.ExpandLaunch map view
  • Distance: 1,281 mi
  • Duration: 10h 55m

What companies run services between Poplar Bluff, MO, USA and Key West, FL, USA?

There is no direct connection from Poplar Bluff to Key West. However, you can take the train to St. Louis, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Key West International Airport (EYW), then take the taxi to Key West. Alternatively, you can take a vehicle from Poplar Bluff to N Roosevelt & 3rd Street via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 34h 52m.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound