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How to get fromPoplar Bluff to Knoxvilleby car, plane, train, or bus

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There are 9 ways to get from Poplar Bluff to Knoxville by car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Jonesboro Municipal Airport, fly to Nashville, drive

    best
    1. Drive from Poplar Bluff to Jonesboro Municipal Airport (JBR)car car
    2. Fly from Jonesboro Municipal Airport (JBR) to Nashville (BNA)plane plane JBR - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 13m
    $164–541

  2. Drive  415.9 mi

    cheapest
    1. Drive from Poplar Bluff to Knoxvillecar car 415.9 mi
    7h 9m
    $76–110

  3. Train, bus

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    44h 3m
    $453–671

  4. Train, bus via Chicago

    1. Take the train from Poplar Bluff Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    45h 45m
    $928–1,479

  5. Drive to Jonesboro Municipal Airport, fly to Mcghee Tyson Airport

    1. Drive from Poplar Bluff to Jonesboro Municipal Airport (JBR)car car
    2. Fly from Jonesboro Municipal Airport (JBR) to Mcghee Tyson Airport (TYS)plane plane JBR - TYS
    5h 38m
    $359–1,291

  6. Drive to Mc Kellar-Sipes Regional Airport, fly to Mcghee Tyson Airport

    1. Drive from Poplar Bluff to Mc Kellar-Sipes Regional Airport (MKL)car car
    2. Fly from Mc Kellar-Sipes Regional Airport (MKL) to Mcghee Tyson Airport (TYS)plane plane MKL - TYS
    7h 24m
    $280–1,206

  7. Train to Lambert–St. Louis International Airport, fly to Nashville, drive

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane plane STL - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    10h 23m
    $263–891

  8. Train, bus via Chicago #2

    1. Take the train from Poplar Bluff Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    46h 23m
    $893–1,356

  9. Drive, bus

    1. Drive from Poplar Bluff to Cape Girardeaucar car
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to New York City Chinatownbus bus
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    47h 8m
    $311–439

Jonesboro Municipal Airport (JBR) to Nashville (BNA) flights

Calendar12Weekly Planes
Duration1h 33mAverage Duration
Ticket$129Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poplar Bluff to Knoxville.ExpandLaunch map view
  • Distance: 474.3 mi
  • Duration: 6h 13m

What companies run services between Poplar Bluff, MO, USA and Knoxville, TN, USA?

There is no direct connection from Poplar Bluff to Knoxville. However, you can drive to Jonesboro Municipal Airport (JBR) airport, fly to Nashville (BNA), then drive to Knoxville. Alternatively, you can take a train from Poplar Bluff Station to Knoxville via St. Louis, St Louis Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 44h 3m.

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