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How to get fromPoplar Bluff to Lexingtonby car, bus, plane, or train

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There are 4 ways to get from Poplar Bluff to Lexington by car, bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus

    best
    1. Drive from Poplar Bluff to Flying J - Matthewscar car
    2. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    15h 29m
    $143–365

  2. Drive 364.3 mi

    cheapest
    1. Drive from Poplar Bluff to Lexingtoncar car 364.3 mi
    6h 15m
    $67–96

  3. Drive, fly

    1. Drive from Poplar Bluff to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Blue Grass Airport (LEX)plane plane PAH - LEX
    11h 37m
    $161–829

  4. Train, bus, drive

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    16h 50m
    $128–235

Barkley Regional Airport (PAH) to Blue Grass Airport (LEX) flights

Calendar21Weekly Planes
Duration8h 33mAverage Duration
Ticket$148Cheapest Price
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Questions & Answers

Map of how to get from Poplar Bluff to Lexington.ExpandLaunch map view
  • Distance: 669.1 mi
  • Duration: 15h 29m

What companies run services between Poplar Bluff, MO, USA and Lexington, KY, USA?

There is no direct connection from Poplar Bluff to Lexington. However, you can drive to Flying J - Matthews, take the bus to Tornado Bus Co - West Memphis, take the bus to La Tropicana - Louisville, KY, walk to Preston @ Vim, take the line 28 bus to W Jefferson @ S 5th, take the line 31 bus to Middletown Station @ Target, then drive to Lexington. Alternatively, you can drive from Poplar Bluff to Lexington in around 6h 15m.

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