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How to get fromPoplar Bluff to Sioux Fallsby car, plane, bus, or train

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There are 6 ways to get from Poplar Bluff to Sioux Falls by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Barkley Regional Airport, fly

    best
    1. Drive from Poplar Bluff to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Sioux Falls (FSD)plane plane PAH - FSD
    8h 47m
    $101–449

  2. Drive, bus

    1. Drive from Poplar Bluff to Cape Girardeaucar car
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    4. Take the bus from Kansas City to Sioux Fallsbus bus
    19h 38m
    $162–254

  3. Train, bus via Kansas City

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the train from St. Louis to Kansas Citytrain train
    3. Take the bus from Kansas City to Sioux Fallsbus bus
    21h 51m
    $220–409

  4. Drive  708.7 mi

    1. Drive from Poplar Bluff to Sioux Fallscar car 708.7 mi
    12h 5m
    $130–187

  5. Train to Lambert–St. Louis International Airport, fly

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Sioux Falls (FSD)plane plane STL - FSD
    11h 32m
    $127–547

  6. Train, bus

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    3. Take the bus from Kansas City to Sioux Fallsbus bus
    20h 54m
    $174–299

Barkley Regional Airport (PAH) to Sioux Falls (FSD) flights

Calendar14Weekly Planes
Duration7h 35mAverage Duration
Ticket$81Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poplar Bluff to Sioux Falls.ExpandLaunch map view
  • Distance: 722.4 mi
  • Duration: 8h 47m

What companies run services between Poplar Bluff, MO, USA and Sioux Falls, SD, USA?

There is no direct connection from Poplar Bluff to Sioux Falls. However, you can drive to Barkley Regional Airport (PAH) airport, fly to Sioux Falls (FSD), walk to 4th Ave/Wells Fargo crosswalk, then take the line 8 bus to Cliff/3rd NW corner. Alternatively, you can take a vehicle from Poplar Bluff to The Bus Stop via Cape Girardeau, St Louis Bus Station, Kansas City Bus Station, Kansas City, Sioux Falls, and Maple/Career NE corner in around 19h 38m.

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