There are 3 ways to get from Port Charlotte to Florida Keys by taxi, ferry, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, ferry
best- Take the taxi from Port Charlotte to Fort Myers Beach, FLtaxi
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
6h 54m$260–287Drive 288.3 mi
cheapest- Drive from Port Charlotte to Florida Keyscar 288.3 mi
5h 58m$53–76Taxi, bus
- Take the taxi from Port Charlotte to Fort Myerstaxi
- Take the bus from Fort Myers to Miami Airportbus
- Take the bus from Miami Airport Station to Big Pine Keybus
9h 46m$169–248
Questions & Answers
The cheapest way to get from Port Charlotte to Florida Keys is to drive which costs $50 - $80 and takes 5h 58m.
The fastest way to get from Port Charlotte to Florida Keys is to drive which takes 5h 58m and costs $50 - $80.
The distance between Port Charlotte and Florida Keys is 198 miles. The road distance is 290 miles.
The best way to get from Port Charlotte to Florida Keys without a car is to taxi and ferry which takes 6h 54m and costs $260 - $290.
It takes approximately 6h 54m to get from Port Charlotte to Florida Keys, including transfers.
Yes, the driving distance between Port Charlotte to Florida Keys is 290 miles. It takes approximately 5h 58m to drive from Port Charlotte to Florida Keys.
There are 965+ hotels available in Florida Keys.
What companies run services between Port Charlotte, FL, USA and Florida Keys, FL, USA?
There is no direct connection from Port Charlotte to Florida Keys. However, you can take the taxi to Fort Myers Beach, FL, take the ferry to Key West, FL, walk to Caroline & Grinnell, take the bus to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take the taxi to Fort Myers, take the bus to Miami Airport, walk to Miami International Airport, take the vehicle to Miami Airport Station, walk to Miami, Airport Intermodal Station, take the bus to Big Pine Key, walk to Big Pine Key - CVS / MM30, take the bus to Sugarloaf Key - Lower - Sugarloaf Lodge, then walk to Florida Keys.
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Fort Myers to Miami Airport
- Ave. Duration
- 2h 55m
- Frequency
- Hourly
- Estimated price
- $40–80
- Website
- https://www.redcoachusa.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–55
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
- Ave. Duration
- 47 min
- Estimated price
- $90–150
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
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