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How to get fromPort Charlotte to Florida Keysby taxi, ferry, bus, car, or plane

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There are 4 ways to get from Port Charlotte to Florida Keys by taxi, ferry, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, ferry

    best
    1. Take the taxi from Port Charlotte to Fort Myers Beach, FLtaxi taxi
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    6h 54m
    $254–280

  2. Drive  288.3 mi

    cheapest
    1. Drive from Port Charlotte to Florida Keyscar car 288.3 mi
    5h 58m
    $53–76

  3. Taxi, bus

    1. Take the taxi from Port Charlotte to Fort Myers Bus Stoptaxi taxi
    2. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    9h 51m
    $125–174

  4. Bus, fly

    1. Take the bus from Port Charlotte Amtrak Bus Stop to Tampabus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    9h 17m
    $175–408

Tampa (TPA) to Key West International Airport (EYW) flights

Calendar12Weekly Planes
Duration1h 34mAverage Duration
Ticket$39Cheapest Price
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Comparing Your Travel Options

Map of how to get from Port Charlotte to Florida Keys.ExpandLaunch map view
  • Distance: 197 mi
  • Duration: 6h 54m

What companies run services between Port Charlotte, FL, USA and Florida Keys, FL, USA?

There is no direct connection from Port Charlotte to Florida Keys. However, you can take the taxi to Fort Myers Beach, FL, take the ferry to Key West, FL, walk to Caroline & Grinnell, take the bus to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take the taxi to Fort Myers Bus Stop, take the bus to Miami Airport Station, take the bus to Big Pine Key, walk to Big Pine Key - CVS / MM30, take the bus to Sugarloaf Key - Lower - Sugarloaf Lodge, then walk to Florida Keys.

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