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How to get fromPort Charlotte to Greenvilleby taxi, plane, bus (Amtrak, Flixbus), car, or bus

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There are 5 ways to get from Port Charlotte to Greenville by taxi, plane, bus (Amtrak, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Ft. Myers, fly to Greenville–Spartanburg International Airport

    best
    1. Take the taxi from Port Charlotte to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Greenville–Spartanburg International Airport (GSP)plane plane RSW - GSP
    2h 53m
    $289–903

  2. Drive 619 mi

    cheapest
    1. Drive from Port Charlotte to Greenvillecar car 619 mi
    12h 29m
    $113–164

  3. Bus

    1. Take the bus from Port Charlotte Amtrak Bus Stop to Tampabus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    18h 13m
    $180–361

  4. Fly Punta Gorda Airport to Asheville Regional Airport, taxi

    1. Fly from Punta Gorda Airport (PGD) to Asheville Regional Airport (AVL)plane plane PGD - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    3h 1m
    $222–561

  5. Line 17 bus to Sarasota–Bradenton International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Venice Train Depot to Downtown Transfer Stationbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Greenville–Spartanburg International Airport (GSP)plane plane SRQ - GSP
    5h 49m
    $193–830

Ft. Myers (RSW) to Greenville–Spartanburg International Airport (GSP) flights

Calendar29Weekly Planes
Duration3h 39mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Port Charlotte to Greenville.ExpandLaunch map view
  • Distance: 634.4 mi
  • Duration: 2h 53m

What companies run services between Port Charlotte, FL, USA and Greenville, SC, USA?

You can take a vehicle from Port Charlotte to Greenville via Port Charlotte Amtrak Bus Stop, Tampa, Nebraska Ave @ Twiggs St, Marion Transit Center, Tampa Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 18h 13m.

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