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How to get fromPort Huron to Florida Keysby train, bus, plane, bus (Amtrak, Greyhound, Flixbus), shuttle, car, or ferry

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There are 9 ways to get from Port Huron to Florida Keys by train, bus, plane, bus (Amtrak, Greyhound, Flixbus), shuttle, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus, train to Detroit, fly to Key West International Airport

    best
    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Take the bus from Flint to Pontiacbus bus
    3. Take the train from Pontiac Amtrak Station to Dearborntrain train
    4. Fly from Detroit (DTW) to Key West International Airport (EYW)plane plane DTW - EYW
    14h 31m
    $257–797

  2. Train, bus, bus to Cleveland-Hopkins International Airport, fly to Key West International Airport

    cheapest
    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Take the bus from Flint to Detroitbus bus
    3. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus bus
    4. Fly from Cleveland-Hopkins International Airport (CLE) to Key West International Airport (EYW)plane plane CLE - EYW
    17h 3m
    $255–711

  3. Bus

    1. Take the bus from Port Huron Station to Flint Amtrak Stationbus bus
    2. Take the bus from Flint to Detroitbus bus
    3. Take the bus from Detroit Bus Station to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 6h

  4. Bus, train, shuttle

    1. Take the bus from Port Huron Station to East Lansing Amtrak Stationbus bus
    2. Take the bus from East Lansing Amtrak Station to Toledobus bus
    3. Take the train from Toledo to Miami Amtrak Stationtrain train
    4. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    2d 8h

  5. Drive  1,534.5 mi

    1. Drive from Port Huron to Florida Keyscar car 1,534.5 mi
    26h 57m
    $281–405

  6. Train, bus, train to Detroit, fly to Miami International Airport, shuttle

    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Take the bus from Flint to Pontiacbus bus
    3. Take the train from Pontiac Amtrak Station to Dearborntrain train
    4. Fly from Detroit (DTW) to Miami International Airport (MIA)plane plane DTW - MIA
    5. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    15h 28m
    $372–787

  7. Train, bus, train to Detroit, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Take the bus from Flint to Pontiacbus bus
    3. Take the train from Pontiac Amtrak Station to Dearborntrain train
    4. Fly from Detroit (DTW) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane DTW - FLL
    5. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    15h 52m
    $412–1,307

  8. Train, bus, bus to Cleveland-Hopkins International Airport, fly to Miami International Airport, shuttle

    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Take the bus from Flint to Detroitbus bus
    3. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus bus
    4. Fly from Cleveland-Hopkins International Airport (CLE) to Miami International Airport (MIA)plane plane CLE - MIA
    5. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    17h 48m
    $410–1,061

  9. Train, bus, train to Detroit, fly to Ft. Myers, ferry

    1. Take the train from Port Huron Station to Flint Amtrak Stationtrain train
    2. Take the bus from Flint to Pontiacbus bus
    3. Take the train from Pontiac Amtrak Station to Dearborntrain train
    4. Fly from Detroit (DTW) to Ft. Myers (RSW)plane plane DTW - RSW
    5. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    18h 17m
    $446–983

Detroit (DTW) to Key West International Airport (EYW) flights

Calendar42Weekly Planes
Duration5h 26mAverage Duration
Ticket$123Cheapest Price
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Comparing Your Travel Options

Map of how to get from Port Huron to Florida Keys.ExpandLaunch map view
  • Distance: 1,385.9 mi
  • Duration: 14h 31m

What companies run services between Port Huron, MI, USA and Florida Keys, FL, USA?

You can take a bus from Port Huron Station to Florida Keys via Flint Amtrak Station, Flint, Detroit Bus Station, Newark Penn Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 2d 6h.

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