There are 8 ways to get from Port Huron to Louisville by train, bus, car, plane, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Port Huron Station to Flint Amtrak Stationtrain
- Take the bus from Flint Amtrak to Detroit Greyhoundbus
- Take the bus from Detroit Bus Station to Louisville Bus Stationbus
12h 20m$117–200Bus
cheapest- Take the bus from Port Huron Station to Flint Amtrak Stationbus
- Take the bus from Flint Amtrak to Detroit Greyhoundbus
- Take the bus from Detroit Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus
13h 50m$73–227Train, bus via Chicago
- Take the train from Port Huron Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville Bus Stationbus
15h 9m$185–387Drive 415.6 mi
- Drive from Port Huron to Louisvillecar 415.6 mi
7h 6m$76–110Train to Bishop International Airport, fly to Louisville International Airport
- Take the train from Port Huron Station to Flint Amtrak Stationtrain
- Fly from Bishop International Airport (FNT) to Louisville International Airport (SDF)plane FNT - SDF
8h 58m$141–568Train, bus to Mbs International Airport, fly to Louisville International Airport
- Take the train from Port Huron Station to Flint Amtrak Stationtrain
- Take the bus from Flint Amtrak to Saginaw Bus Centerbus
- Fly from Mbs International Airport (MBS) to Louisville International Airport (SDF)plane MBS - SDF
9h 41m$125–548Train, bus to Detroit, fly to Louisville International Airport
- Take the train from Port Huron Station to East Lansing Amtrak Stationtrain
- Take the bus from East Lansing Marriott to DTW McNamara Terminalbus
- Fly from Detroit (DTW) to Louisville International Airport (SDF)plane DTW - SDF
9h 38m$128–662Train, bus to Detroit, fly to Blue Grass Airport, drive
- Take the train from Port Huron Station to East Lansing Amtrak Stationtrain
- Take the bus from East Lansing Marriott to DTW McNamara Terminalbus
- Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane DTW - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
9h 43m$180–928
Port Huron to Louisville by train and bus
Questions & Answers
The cheapest way to get from Port Huron to Louisville is to drive which costs $75 - $110 and takes 7h 6m.
The fastest way to get from Port Huron to Louisville is to drive which takes 7h 6m and costs $75 - $110.
No, there is no direct bus from Port Huron station to Louisville station. However, there are services departing from Port Huron Station and arriving at Louisville, KY Bus Station via Flint Amtrak, Detroit Bus Station and N Wilson Rd & Ferrell Pl - Columbus. The journey, including transfers, takes approximately 13h 50m.
The distance between Port Huron and Louisville is 484 miles. The road distance is 418 miles.
The best way to get from Port Huron to Louisville without a car is to train and bus which takes 12h 20m and costs $110 - $200.
It takes approximately 12h 20m to get from Port Huron to Louisville, including transfers.
Port Huron to Louisville bus services, operated by Amtrak, depart from Port Huron Station.
Port Huron to Louisville bus services, operated by Amtrak, arrive at Flint Amtrak Station.
Yes, the driving distance between Port Huron to Louisville is 418 miles. It takes approximately 7h 6m to drive from Port Huron to Louisville.
There are 561+ hotels available in Louisville.
What companies run services between Port Huron, MI, USA and Louisville, KY, USA?
You can take a bus from Port Huron Station to Louisville, KY Bus Station via Flint Amtrak, Detroit Bus Station, and N Wilson Rd & Ferrell Pl - Columbus in around 13h 50m.
- Website
- delta.com
Flights from Mbs International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $75–450
Flights from Detroit to Louisville International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $80–550
Flights from Detroit to Blue Grass Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $120–800
- Website
- united.com
Flights from Bishop International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $85–480
Flights from Mbs International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $85–480
- Website
- southwest.com
Flights from Bishop International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 7h 5m
- When
- Thursday
- Estimated price
- $100–550
Flights from Detroit to Louisville International Airport via Nashville
- Ave. Duration
- 3h 45m
- When
- Sunday
- Estimated price
- $110–650
- Website
- aa.com
Flights from Bishop International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 11h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $20–45
- Website
- https://www.amtrak.com/home.html
Train from Port Huron Station to Chicago Union Station
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- $100–210
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
Train from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $20–45
- Website
- https://www.amtrak.com/home.html
Train from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $20–45
- Website
- https://www.amtrak.com/home.html
Train from Port Huron Station to East Lansing Amtrak Station
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.amtrak.com/home.html
Train from Port Huron Station to East Lansing Amtrak Station
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 989-725-5105
- Website
- indiantrails.com
Bus from Flint Amtrak to Detroit Greyhound
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $12–27
- Website
- https://indiantrails.com
Bus from Flint Amtrak to Detroit Greyhound
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $12–27
- Website
- https://indiantrails.com
Bus from Flint Amtrak to Saginaw Bus Center
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $7–21
- Website
- https://indiantrails.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Flint Amtrak to Detroit Greyhound
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $25–40
Bus from Detroit Bus Station to Louisville Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- $85–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $85–120
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $35–50
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–50
Bus from Flint Amtrak to Detroit Greyhound
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $25–40
Bus from Detroit Bus Station to N Wilson Rd & Ferrell Pl - Columbus
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
Bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Station
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $55–80
- Book at
- https://www.jeffersonlines.com
- Adult
- $55–80
Bus from Flint Amtrak to Saginaw Bus Center
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $20–28
- Book at
- https://www.jeffersonlines.com
- Adult
- $20–28
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Detroit Bus Station to Louisville Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a day
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 15m
- Frequency
- Once a week
- Estimated price
- $23–35
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Detroit Bus Station to N Wilson Rd & Ferrell Pl - Columbus
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Station
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- https://baronsbus.com
- Phone
- +1 517-333-0400
- [email protected]
- Website
- michiganflyer.com
Bus from East Lansing Marriott to DTW McNamara Terminal
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- $9–35
- Website
- https://www.michiganflyer.com/
- Child 2-16
- $9–11
- Adult
- $22–35
Bus from East Lansing Marriott to DTW McNamara Terminal
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- $9–35
- Website
- https://www.michiganflyer.com/
- Child 2-16
- $9–11
- Adult
- $22–35
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide














