There are 8 ways to get from Port Huron to Louisville by bus (Amtrak), train, bus, car, plane, or bus (Flixbus, Greyhound, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Chicago (Amtrak)
best- Take the bus from Port Huron Station to Chicago Union Stationbus Amtrak Thruway Connecting Service
- Take the bus from Chicago Union Station to Louisville, KYbus Chicago
14h 10mDrive 415.6 mi
cheapest- Drive from Port Huron to Louisvillecar 415.6 mi
7h 6m$71–103Train, bus (Amtrak)
- Take the train from Port Huron Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
15h 14m$296–482Train, bus to Mbs International Airport, fly to Louisville International Airport
- Take the train from Port Huron Station to Flint Amtrak Stationtrain
- Take the bus from Flint to Bay Citybus
- Fly from Mbs International Airport (MBS) to Louisville International Airport (SDF)plane MBS - SDF
9h 20m$169–759Bus
- Take the bus from Sarnia to Londonbus
- Take the bus from London to Detroit Bus Stationbus
- Take the bus from Detroit Bus Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
16h 5m$102–170Bus to Toronto Pearson International Airport, fly to Louisville International Airport
- Take the bus from Sarnia to Toronto Pearson Airportbus
- Fly from Toronto Pearson International Airport (YYZ) to Louisville International Airport (SDF)plane YYZ - SDF
9h 6m$131–697Train, bus, train to Detroit, fly to Louisville International Airport
- Take the train from Port Huron Station to Flint Amtrak Stationtrain
- Take the bus from Flint to Pontiacbus
- Take the train from Pontiac Amtrak Station to Dearborntrain
- Fly from Detroit (DTW) to Louisville International Airport (SDF)plane DTW - SDF
9h 31m$201–1,056Train, bus, train to Detroit, fly to Blue Grass Airport, drive
- Take the train from Port Huron Station to Flint Amtrak Stationtrain
- Take the bus from Flint to Pontiacbus
- Take the train from Pontiac Amtrak Station to Dearborntrain
- Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane DTW - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
9h 35m$147–621
Mbs International Airport (MBS) to Louisville International Airport (SDF) flights
Comparing Your Travel Options
The cheapest way to get from Port Huron to Louisville is to drive which costs $70 - $110 and takes 7h 6m.
The fastest way to get from Port Huron to Louisville is to drive which takes 7h 6m and costs $70 - $110.
No, there is no direct bus from Port Huron station to Louisville. However, there are services departing from Port Huron Station and arriving at Louisville, KY via Chicago Union Station. The journey, including transfers, takes approximately 14h 10m.
The distance between Port Huron and Louisville is 651 miles. The road distance is 418 miles.
The best way to get from Port Huron to Louisville without a car is to bus via Chicago which takes 14h 10m and costs .
It takes approximately 14h 10m to get from Port Huron to Louisville, including transfers.
Port Huron to Louisville bus services, operated by Flixbus USA, depart from Sarnia station.
Port Huron to Louisville bus services, operated by Flixbus USA, arrive at London station.
Yes, the driving distance between Port Huron to Louisville is 418 miles. It takes approximately 7h 6m to drive from Port Huron to Louisville.
Book your Port Huron to Louisville bus tickets online with Omio.
What companies run services between Port Huron, MI, USA and Louisville, KY, USA?
You can take a bus from Port Huron Station to Louisville, KY via Chicago Union Station in around 14h 10m.
- Website
- delta.com
Flights from Mbs International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $100–650
Flights from Toronto Pearson International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $100–650
Flights from Detroit to Louisville International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $140–950
Flights from Detroit to Blue Grass Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $75–500
- Website
- united.com
Flights from Mbs International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $110–700
Flights from Toronto Pearson International Airport to Louisville International Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Wednesday, Thursday, and Sunday
- Estimated price
- $100–650
- Website
- aircanada.com
Flights from Toronto Pearson International Airport to Louisville International Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Wednesday, Thursday, and Sunday
- Estimated price
- $100–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Port Huron Station to Chicago Union Station
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- $170–270
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $100–170
- Website
- Amtrak
Train from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Amtrak
Train from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Amtrak
Train from Pontiac Amtrak Station to Dearborn
- Ave. Duration
- 59 min
- Frequency
- 3 times a day
- Estimated price
- $17–28
- Website
- Amtrak
Train from Port Huron Station to Flint Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Amtrak
Train from Pontiac Amtrak Station to Dearborn
- Ave. Duration
- 59 min
- Frequency
- 3 times a day
- Estimated price
- $17–28
- Website
- Amtrak
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Port Huron Station to Chicago Union Station
- Ave. Duration
- 6h 25m
- Frequency
- Once a week
- Website
- Amtrak
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Flint to Bay City
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $9–24
- Website
- Indian Trails
Bus from Flint to Pontiac
- Ave. Duration
- 55 min
- Frequency
- Twice daily
- Estimated price
- $7–21
- Website
- Indian Trails
Bus from Flint to Pontiac
- Ave. Duration
- 55 min
- Frequency
- Twice daily
- Estimated price
- $7–21
- Website
- Indian Trails
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Sarnia to London
- Ave. Duration
- 1h 40m
- Frequency
- 3 times a day
- Estimated price
- $10–15
- Schedules at
- Flixbus USA
Bus from London to Detroit Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- Every 4 hours
- Estimated price
- $20–30
- Schedules at
- Flixbus USA
Bus from Sarnia to Toronto Pearson Airport
- Ave. Duration
- 4h 20m
- Frequency
- 3 times a day
- Estimated price
- $29–45
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Detroit Bus Station to Indianapolis Union Station
- Ave. Duration
- 5h 35m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
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