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How to get fromPort Isabel to Cancúnby plane, bus, or car

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There are 7 ways to get from Port Isabel to Cancún by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Servando Canales International Airport

    best
    1. Fly from General Servando Canales International Airport (MAM) to Cancún International Airport (CUN)plane plane MAM - CUN
    7h 26m
    $1,917–7,227

  2. Bus, bus to General Lucio Blanco International Airport, fly

    cheapest
    1. Take the bus from Las Palmas Port Isabel to La Plaza at Brownsvillebus bus
    2. Take the bus from Brownsville to McAllen Central Stationbus bus
    3. Fly from General Lucio Blanco International Airport (REX) to Cancún International Airport (CUN)plane plane REX - CUN
    7h 12m
    $1,562–9,742

  3. Bus

    1. Take the bus from Matamoros to Veracruzbus bus
    2. Take the bus from Veracruz to Terminal de Autobuses ADO Cancúnbus bus
    42h
    $3,644–6,449

  4. Drive  2,242.9 km

    1. Drive from Port Isabel to Cancúncar car 2,242.9 km
    28h 2m
    $4,688–6,772

  5. Fly from Brownsville-South Padre Island International Airport

    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Cancún International Airport (CUN)plane plane BRO - CUN
    8h 18m
    $1,572–7,657

  6. Bus to Mcallen Miller International Airport, fly

    1. Take the bus from Brownsville to McAllen Central Stationbus bus
    2. Fly from Mcallen Miller International Airport (MFE) to Cancún International Airport (CUN)plane plane MFE - CUN
    10h 6m
    $1,702–8,777

  7. Bus to Rio Grande Valley International Airport, fly

    1. Take the bus from Brownsville to Harlingen Bus Stationbus bus
    2. Fly from Rio Grande Valley International Airport (HRL) to Cancún International Airport (CUN)plane plane HRL - CUN
    10h 38m
    $2,309–8,644

General Servando Canales International Airport (MAM) to Cancún International Airport (CUN) flights

Calendar5Weekly Planes
Duration5h 16mAverage Duration
Ticket$1,795Cheapest Price
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Comparing Your Travel Options

Map of how to get from Port Isabel to Cancún.ExpandLaunch map view
  • Distance: 1,268.5 km
  • Duration: 7h 26m

What companies run services between Port Isabel, TX, USA and Cancún, Mexico?

Viva Aerobus and Aeroméxico fly from General Servando Canales International Airport (MAM) to Cancún International Airport (CUN) 5 times a week. Alternatively, you can take a bus from Las Palmas Port Isabel to Terminal de Autobuses ADO Cancún via La Plaza at Brownsville, Matamoros(Hotel Los Lirios), Matamoros, and Veracruz in around 42h.

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