Rome2Rio

How to get fromPort Orange to Florida Keysby taxi, plane, bus, train, shuttle, car, or bus (Flixbus, Greyhound)

Find Transport to Florida Keys

See all options

There are 5 ways to get from Port Orange to Florida Keys by taxi, plane, bus, train, shuttle, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly, bus

    best
    1. Take the taxi from Port Orange to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    4h 58m
    $190–426

  2. Bus

    cheapest
    1. Take the bus from Daytona Beach to Miami Airport Stationbus bus FlixBus 2431
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    16h 30m
    $70–123

  3. Taxi, train, bus

    1. Take the taxi from Port Orange to DeLandtaxi taxi
    2. Take the train from DeLand to Sand Lake Roadtrain train
    3. Take the train from Orlando to Miamitrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    13h 6m
    $170–346

  4. Bus, shuttle

    1. Take the bus from Daytona Beach to Miami Airport Stationbus bus FlixBus 2431
    2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    16h 8m
    $201–263

  5. Drive 395.5 mi

    1. Drive from Port Orange to Florida Keyscar car 395.5 mi
    7h 14m
    $73–105

Port Orange to Florida Keys by bus, tram, shuttle, and foot

Calendar4Weekly Services
Duration16h 8mAverage Duration
Ticket$201Cheapest Price
See schedules

Questions & Answers

Map of how to get from Port Orange to Florida Keys.ExpandLaunch map view
  • Distance: 349.1 mi
  • Duration: 4h 58m

What companies run services between Port Orange, FL, USA and Florida Keys, FL, USA?

You can take a bus from Church ST. & US 1 Ib to Florida Keys via Transfer Plaza, Daytona Beach, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 16h 30m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound