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How to get fromPort Saint Lucie to Appletonby bus, plane, bus (Flixbus, Greyhound), train, or car

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There are 8 ways to get from Port Saint Lucie to Appleton by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Orlando, fly to Appleton International Airport

    best
    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Appleton International Airport (ATW)plane plane MCO - ATW
    7h 43m
    $218–911

  2. Bus

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus
    32h 50m
    $255–446

  3. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus
    2d 1h
    $611–1,291

  4. Drive 1,411.1 mi

    1. Drive from Port Saint Lucie to Appletoncar car 1,411.1 mi
    24h 55m
    $258–372

  5. Bus to Fort Lauderdale–Hollywood International Airport, fly to Appleton International Airport

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Appleton International Airport (ATW)plane plane FLL - ATW
    7h 9m
    $265–1,061

  6. Drive to Orlando Sanford, fly to Appleton International Airport

    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Appleton International Airport (ATW)plane plane SFB - ATW
    5h 43m
    $228–953

  7. Bus to President Donald J. Trump International Airport, fly to Appleton International Airport

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Appleton International Airport (ATW)plane plane PBI - ATW
    8h 42m
    $299–1,259

  8. Bus to Orlando, fly to General Mitchell International Airport, bus

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to General Mitchell International Airport (MKE)plane plane MCO - MKE
    3. Take the bus from Milwaukee Airport to Appletonbus bus
    11h
    $221–672

Port Saint Lucie to Appleton by bus, train, and foot

Calendar5Weekly Services
Duration2d 1hAverage Duration
Ticket$611Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Appleton.ExpandLaunch map view
  • Distance: 1,304 mi
  • Duration: 7h 43m

What companies run services between Port Saint Lucie, FL, USA and Appleton, WI, USA?

You can take a vehicle from Port Saint Lucie to Appleton Transit Center via Port St Lucie, Atlanta Bus Station, and Chicago Bus Station in around 32h 50m.

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