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How to get fromPort Saint Lucie to Appletonby car, plane, bus (Flixbus, Greyhound), bus, or train

Find Transport to Appleton

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There are 7 ways to get from Port Saint Lucie to Appleton by car, plane, bus (Flixbus, Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly

    best
    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Appleton International Airport (ATW)plane plane SFB - ATW
    5h 36m
    $138–543

  2. Bus

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus
    32h 50m
    $239–391

  3. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus
    2d 1h
    $480–1,086

  4. Drive  1,409.6 mi

    1. Drive from Port Saint Lucie to Appletoncar car 1,409.6 mi
    24h 55m
    $258–372

  5. Bus to Orlando, fly

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Appleton International Airport (ATW)plane plane MCO - ATW
    7h 31m
    $143–531

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Appleton International Airport (ATW)plane plane FLL - ATW
    7h 9m
    $165–661

  7. Bus to President Donald J. Trump International Airport, fly

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Appleton International Airport (ATW)plane plane PBI - ATW
    9h 42m
    $169–659

Port Saint Lucie to Appleton by bus, train, and foot

Calendar5Weekly Services
Duration2d 1hAverage Duration
Ticket$480Cheapest Price
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Comparing Your Travel Options

Map of how to get from Port Saint Lucie to Appleton.ExpandLaunch map view
  • Distance: 1,278.8 mi
  • Duration: 5h 36m

What companies run services between Port Saint Lucie, FL, USA and Appleton, WI, USA?

You can take a vehicle from Port Saint Lucie to Appleton Transit Center via Port St Lucie, Atlanta Bus Station, and Chicago Bus Station in around 32h 50m.

Airlines
Train operators
Bus operators

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