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How to get fromPort Saint Lucie to Beaufortby bus, plane, car, train, or taxi

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There are 9 ways to get from Port Saint Lucie to Beaufort by bus, plane, car, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to President Donald J. Trump International Airport, fly to Charleston International Airport, drive

    best
    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Charleston International Airport (CHS)plane plane PBI - CHS
    3. Drive from Charleston-Airport-CHS to Beaufortcar car
    6h 23m
    $157–810

  2. Drive 410.4 mi

    cheapest
    1. Drive from Port Saint Lucie to Beaufortcar car 410.4 mi
    6h 57m
    $75–109

  3. Bus, train, taxi

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Savannah Stationtrain train
    3. Take the taxi from Savannah Station to Beauforttaxi taxi
    11h 39m
    $312–471

  4. Bus, train, taxi via Jacksonville

    1. Take the bus from Fort Pierce to Jacksonvillebus bus
    2. Take the train from Jacksonville to Savannah Stationtrain train
    3. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    4. Take the bus from Bluffton Transfer Center to Beaufort County Magistrate Courtbus bus 302
    15h 24m

  5. Bus to Miami International Airport, fly to Savannah, taxi

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Miami International Airport (MIA) to Savannah (SAV)plane plane MIA - SAV
    3. Take the taxi from Savannah (SAV) to Beauforttaxi taxi
    6h 26m
    $283–694

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly to Charleston International Airport, drive

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    3. Drive from Charleston-Airport-CHS to Beaufortcar car
    6h 37m
    $213–1,162

  7. Bus to Miami International Airport, fly to Charleston International Airport, drive

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    3. Drive from Charleston-Airport-CHS to Beaufortcar car
    7h 4m
    $545–1,063

  8. Bus to Orlando, fly to Charleston International Airport, drive

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Charleston International Airport (CHS)plane plane MCO - CHS
    3. Drive from Charleston-Airport-CHS to Beaufortcar car
    7h 12m
    $111–312

  9. Bus, train, taxi via DeLand

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Sand Lake Road to DeLandtrain train
    3. Take the train from Deland to Savannah Stationtrain train
    4. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    5. Take the bus from Bluffton Transfer Center to Beaufort County Magistrate Courtbus bus 302
    13h 28m

President Donald J. Trump International Airport (PBI) to Charleston International Airport (CHS) flights

Calendar27Weekly Planes
Duration3h 36mAverage Duration
Ticket$94Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Beaufort.ExpandLaunch map view
  • Distance: 561.7 mi
  • Duration: 6h 23m

What companies run services between Port Saint Lucie, FL, USA and Beaufort, SC, USA?

There is no direct connection from Port Saint Lucie to Beaufort. However, you can take the taxi to GATLIN BLVD at I-95 P/R LOT, take the bus to WPB ITC at TRI RAIL, walk to WPB ITC at BAY L, take the line 44 bus to TURNAGE BLVD at PBI TRM, walk to President Donald J. Trump International Airport (PBI) airport, fly to Charleston International Airport (CHS), then drive to Beaufort. Alternatively, you can take the bus to Kissimmee -1471 East Osceola Parkway, walk to Osceola Pkwy Walmart, take the line 18 bus to Pleasant St & Neptune Rd, walk to Kissimmee Amtrak Station, take the train to Savannah Station, then take the taxi to Beaufort.

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