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How to get fromPort Saint Lucie to Biloxiby bus, plane, bus (Greyhound, Flixbus), car, taxi, train, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Port Saint Lucie to Biloxi by bus, plane, bus (Greyhound, Flixbus), car, taxi, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Orlando, fly to Gulfport-Biloxi Regional Airport

    best
    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Gulfport-Biloxi Regional Airport (GPT)plane plane MCO - GPT
    6h 32m
    $189–738

  2. Bus via Orlando

    cheapest
    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the bus from Orlando to Tallahasseebus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    18h 53m
    $115–207

  3. Bus

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    18h 4m
    $140–262

  4. Drive 669.3 mi

    1. Drive from Port Saint Lucie to Biloxicar car 669.3 mi
    10h 53m
    $123–177

  5. Bus to President Donald J. Trump International Airport, fly to Gulfport-Biloxi Regional Airport

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Gulfport-Biloxi Regional Airport (GPT)plane plane PBI - GPT
    7h 54m
    $180–686

  6. Bus, taxi to Melbourne International Airport, fly to Gulfport-Biloxi Regional Airport

    1. Take the bus from Fort Pierce to Sebastianbus bus
    2. Take the taxi from Sebastian to Melbourne International Airport (MLB)taxi taxi
    3. Fly from Melbourne International Airport (MLB) to Gulfport-Biloxi Regional Airport (GPT)plane plane MLB - GPT
    10h 1m
    $220–644

  7. Bus to Fort Lauderdale–Hollywood International Airport, fly to Louis Armstrong New Orleans International Airport, train

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Louis Armstrong New Orleans International Airport (MSY)plane plane FLL - MSY
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    9h 16m
    $319–1,403

Port Saint Lucie to Biloxi by bus

Calendar5Weekly Buses
Duration18h 53mAverage Duration
Ticket$115Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Biloxi.ExpandLaunch map view
  • Distance: 635.7 mi
  • Duration: 6h 32m

What companies run services between Port Saint Lucie, FL, USA and Biloxi, MS, USA?

You can take a bus from Fort Pierce to Biloxi Transit Center via Kissimmee -1471 East Osceola Parkway, Old St Augustine at Intramural Field, Tallahassee, and Mobile Bus Station in around 18h 4m.

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