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How to get fromPort Saint Lucie to Buffaloby taxi, plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 7 ways to get from Port Saint Lucie to Buffalo by taxi, plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Vero Beach Municipal Airport, fly

    best
    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Buffalo Niagara International Airport (BUF)plane plane VRB - BUF
    7h 52m
    $248–887

  2. Bus to Fort Lauderdale–Hollywood International Airport, fly

    cheapest
    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Buffalo Niagara International Airport (BUF)plane plane FLL - BUF
    7h 24m
    $206–921

  3. Bus

    1. Take the bus from Fort Pierce to Fort Lauderdale - Broward Blvd Park and Ridebus bus
    2. Take the bus from Ft Lauderdale Broward Park & Ride to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Buffalobus bus
    36h 13m
    $290–458

  4. Bus, train via New York

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    36h 24m
    $872–1,411

  5. Drive  1,266.2 mi

    1. Drive from Port Saint Lucie to Buffalocar car 1,266.2 mi
    21h 19m
    $217–313

  6. Bus to Orlando, fly

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Buffalo Niagara International Airport (BUF)plane plane MCO - BUF
    7h 52m
    $219–451

  7. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    42h 16m
    $727–1,331

Port Saint Lucie to Buffalo by bus

Calendar7Weekly Buses
Duration36h 13mAverage Duration
Ticket$290Cheapest Price
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Comparing Your Travel Options

Map of how to get from Port Saint Lucie to Buffalo.ExpandLaunch map view
  • Distance: 1,097 mi
  • Duration: 7h 52m

What companies run services between Port Saint Lucie, FL, USA and Buffalo, NY, USA?

You can take a bus from Fort Pierce to Buffalo via Fort Lauderdale - Broward Blvd Park and Ride, Ft Lauderdale Broward Park & Ride, and Newark Penn Station in around 36h 13m.

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