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How to get fromPort Saint Lucie to Chicagoby bus, plane, bus (Greyhound, Flixbus), train, or car

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There are 9 ways to get from Port Saint Lucie to Chicago by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Orlando, fly to Chicago Midway International Airport

    best
    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Chicago Midway International Airport (MDW)plane plane MCO - MDW
    6h 37m
    $232–549

  2. Bus to Orlando, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Chicago O'Hare International Airport (ORD)plane plane MCO - ORD
    7h
    $102–659

  3. Bus

    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Take the bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Stationbus bus
    3. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    25h 30m
    $251–485

  4. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus Miami to Orlando / ...
    2. Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain train Floridian
    43h 30m
    $578–1,250

  5. Drive 1,222.3 mi

    1. Drive from Port Saint Lucie to Chicagocar car 1,222.3 mi
    21h 28m
    $224–323

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Fort Pierce to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Chicago Midway International Airport (MDW)plane plane FLL - MDW
    6h 28m
    $125–497

  7. Bus to Fort Lauderdale–Hollywood International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Fort Pierce to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Chicago O'Hare International Airport (ORD)plane plane FLL - ORD
    7h
    $235–647

  8. Bus to Orlando, fly to General Mitchell International Airport, train

    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to General Mitchell International Airport (MKE)plane plane MCO - MKE
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    8h 58m
    $219–678

  9. Bus, bus to President Donald J. Trump International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Fort Pierce to Pompano Beach Service Plazabus bus
    2. Take the bus from Pompano Beach, FL - Travel Plaza to West Palm Beach, FLbus bus
    3. Fly from President Donald J. Trump International Airport (PBI) to Chicago O'Hare International Airport (ORD)plane plane PBI - ORD
    9h 20m
    $142–513

Port Saint Lucie to Chicago by bus and subway

Calendar7Weekly Services
Duration25h 30mAverage Duration
Ticket$251Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Chicago.ExpandLaunch map view
  • Distance: 1,131.7 mi
  • Duration: 6h 37m

What companies run services between Port Saint Lucie, FL, USA and Chicago, IL, USA?

You can take a bus from Fort Pierce to Chicago Bus Station via Orlando RedCoach Station, Atlanta - Civic Center MARTA Station, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 25h 30m.

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