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How to get fromPort Saint Lucie to Columbiaby taxi, plane, bus, train, bus (Greyhound), or car

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There are 5 ways to get from Port Saint Lucie to Columbia by taxi, plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Vero Beach Municipal Airport, fly

    best
    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Columbia (CAE)plane plane VRB - CAE
    5h 59m
    $174–551

  2. Bus

    cheapest
    1. Take the bus from Fort Pierce to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    3. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus bus 44
    18h 37m
    $82–158

  3. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus Miami to Orlando
    2. Take the train from Kissimmee Amtrak Station to Columbia Stationtrain train Floridian
    13h 56m
    $172–341

  4. Drive 521.3 mi

    1. Drive from Port Saint Lucie to Columbiacar car 521.3 mi
    8h 35m
    $96–138

  5. Bus to President Donald J. Trump International Airport, fly

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Columbia (CAE)plane plane PBI - CAE
    8h 29m
    $122–493

Port Saint Lucie to Columbia by bus and train

Calendar7Weekly Services
Duration13h 56mAverage Duration
Ticket$172Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Columbia.ExpandLaunch map view
  • Distance: 472.9 mi
  • Duration: 5h 59m

What companies run services between Port Saint Lucie, FL, USA and Columbia, SC, USA?

You can take a bus from SW Airoso Blvd & Crosstown Pkwy to Assembly Senate North via Avenue D & N 8th St, Wheeler Ter & Okeechobee Rd, Fort Pierce, Jacksonville, Sumter Bus Stop, and James E Clyburn Intermodal Transportation Center in around 18h 37m.

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