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How to get fromPort Saint Lucie to Destinby car, plane, bus, or taxi

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There are 8 ways to get from Port Saint Lucie to Destin by car, plane, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Melbourne International Airport, fly to Destin–Fort Walton Beach Airport

    best
    1. Drive from Port Saint Lucie to Melbourne International Airport (MLB)car car
    2. Fly from Melbourne International Airport (MLB) to Destin–Fort Walton Beach Airport (VPS)plane plane MLB - VPS
    5h 29m
    $126–451

  2. Drive 498.3 mi

    cheapest
    1. Drive from Port Saint Lucie to Destincar car 498.3 mi
    9h 10m
    $91–132

  3. Bus, taxi via Sandy Springs

    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Take the bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Stationbus bus
    3. Take the bus from Atlanta to Mobilebus bus
    4. Take the bus from Loxley to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    19h 31m
    $336–520

  4. Bus to Miami International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Destin–Fort Walton Beach Airport (VPS)plane plane MIA - VPS
    5h 33m
    $126–415

  5. Bus to Orlando, fly to Pensacola International Airport, taxi

    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Pensacola International Airport (PNS)plane plane MCO - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    5h 58m
    $235–1,114

  6. Bus to Miami International Airport, fly to Pensacola International Airport, taxi

    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Pensacola International Airport (PNS)plane plane MIA - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    6h 30m
    $201–490

  7. Bus, taxi

    1. Take the bus from Fort Pierce to Tallahassee FSUbus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    20h 4m
    $262–421

  8. Bus, taxi #2

    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Take the bus from Orlando to Tallahasseebus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    21h 7m
    $235–374

Melbourne International Airport (MLB) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar36Weekly Planes
Duration5h 23mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Destin.ExpandLaunch map view
  • Distance: 471.9 mi
  • Duration: 5h 29m

What companies run services between Port Saint Lucie, FL, USA and Destin, FL, USA?

There is no direct connection from Port Saint Lucie to Destin. However, you can drive to Melbourne International Airport (MLB) airport, fly to Destin–Fort Walton Beach Airport (VPS), then take the taxi to Destin. Alternatively, you can take the bus to Orlando RedCoach Station, take the bus to Atlanta - Civic Center MARTA Station, walk to Civic Center Station, take the subway to Doraville Station, walk to Atlanta, take the bus to Mobile, take the bus to Crestview, then take the taxi to Destin.

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