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How to get fromPort Saint Lucie to Durhamby bus, plane, bus (Flixbus), train, car, or taxi

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There are 9 ways to get from Port Saint Lucie to Durham by bus, plane, bus (Flixbus), train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Fort Lauderdale–Hollywood International Airport, fly to Raleigh-Durham International Airport

    best
    1. Take the bus from Fort Pierce to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Raleigh-Durham International Airport (RDU)plane plane FLL - RDU
    6h 15m
    $199–898

  2. Bus to Orlando, fly to Raleigh-Durham International Airport

    cheapest
    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Raleigh-Durham International Airport (RDU)plane plane MCO - RDU
    6h 18m
    $101–350

  3. Bus

    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus Miami–Tallahassee via Orlando
    2. Take the bus from Orlando Bus Station to Raleigh Bus Stationbus bus FlixBus N2472
    16h 49m
    $128–221

  4. Bus, train

    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus Miami–Tallahassee via Orlando
    2. Take the train from Winter Park Amtrak Station to Raleigh Union Stationtrain train Floridian
    19h 48m
    $233–477

  5. Drive 688.7 mi

    1. Drive from Port Saint Lucie to Durhamcar car 688.7 mi
    12h 2m
    $126–182

  6. Taxi to Vero Beach Municipal Airport, fly to Raleigh-Durham International Airport

    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Raleigh-Durham International Airport (RDU)plane plane VRB - RDU
    4h 8m
    $238–915

  7. Bus to Miami International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Raleigh-Durham International Airport (RDU)plane plane MIA - RDU
    6h 58m
    $157–746

  8. Drive to Melbourne International Airport, fly to Charlotte Douglas International Airport, train

    1. Drive from Port Saint Lucie to Melbourne International Airport (MLB)car car
    2. Fly from Melbourne International Airport (MLB) to Charlotte Douglas International Airport (CLT)plane plane MLB - CLT
    3. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    7h 53m
    $150–672

  9. Bus, bus to President Donald J. Trump International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Fort Pierce to Pompano Beach Service Plazabus bus
    2. Take the bus from Pompano Beach, FL - Travel Plaza to West Palm Beach, FLbus bus
    3. Fly from President Donald J. Trump International Airport (PBI) to Raleigh-Durham International Airport (RDU)plane plane PBI - RDU
    8h 48m
    $101–344

Port Saint Lucie to Durham by bus

Calendar12Weekly Buses
Duration16h 49mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Durham.ExpandLaunch map view
  • Distance: 791.2 mi
  • Duration: 6h 15m

What companies run services between Port Saint Lucie, FL, USA and Durham, NC, USA?

You can take a bus from Fort Pierce to Durham via Orlando RedCoach Station, Mccoy Rd & Gondola Dr, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Raleigh Bus Station in around 16h 49m.

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