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How to get fromPort Saint Lucie to Durhamby taxi, plane, bus (Flixbus), bus, train, or car

Find Transport to Durham

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There are 6 ways to get from Port Saint Lucie to Durham by taxi, plane, bus (Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Vero Beach Municipal Airport, fly

    best
    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Raleigh-Durham International Airport (RDU)plane plane VRB - RDU
    4h 8m
    $188–665

  2. Bus to Orlando, fly

    cheapest
    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Raleigh-Durham International Airport (RDU)plane plane MCO - RDU
    7h 29m
    $100–359

  3. Bus

    1. Take the bus from Fort Pierce to Orlandobus bus Miami to Orlando
    2. Take the bus from Orlando Bus Station to Raleigh Bus Stationbus bus FlixBus N2472
    17h 19m
    $131–199

  4. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus Miami to Orlando
    2. Take the train from Kissimmee Amtrak Station to Carytrain train Floridian
    19h 28m
    $391–607

  5. Drive  688.7 mi

    1. Drive from Port Saint Lucie to Durhamcar car 688.7 mi
    12h 3m
    $126–182

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Raleigh-Durham International Airport (RDU)plane plane FLL - RDU
    7h
    $167–499

Port Saint Lucie to Durham by bus

Calendar5Weekly Buses
Duration17h 19mAverage Duration
Ticket$131Cheapest Price
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Comparing Your Travel Options

Map of how to get from Port Saint Lucie to Durham.ExpandLaunch map view
  • Distance: 620.1 mi
  • Duration: 4h 8m

What companies run services between Port Saint Lucie, FL, USA and Durham, NC, USA?

You can take a bus from Fort Pierce to Durham via L B Mcleod Rd & Gardenia Ave, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Raleigh Bus Station in around 17h 19m.

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