What is the cheapest way to get from Port Saint Lucie to Florida Keys?

The cheapest way to get from Port Saint Lucie to Florida Keys is to drive which costs $45 - $70 and takes 5h 1m.

What is the fastest way to get from Port Saint Lucie to Florida Keys?

The fastest way to get from Port Saint Lucie to Florida Keys is to drive which takes 5h 1m and costs $45 - $70.

Is there a direct bus between Port Saint Lucie and Florida Keys?

No, there is no direct bus from Port Saint Lucie to Florida Keys. However, there are services departing from Fort Pierce and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 8h 30m.

How far is it from Port Saint Lucie to Florida Keys?

The distance between Port Saint Lucie and Florida Keys is 262 miles. The road distance is 258.7 miles.

How do I travel from Port Saint Lucie to Florida Keys without a car?

The best way to get from Port Saint Lucie to Florida Keys without a car is to bus which takes 8h 30m and costs $50 - $85.

How long does it take to get from Port Saint Lucie to Florida Keys?

It takes approximately 8h 30m to get from Port Saint Lucie to Florida Keys, including transfers.

Where do I catch the Port Saint Lucie to Florida Keys bus from?

Port Saint Lucie to Florida Keys bus services, operated by RedCoach, depart from Fort Pierce station.

Where does the Port Saint Lucie to Florida Keys bus arrive?

Port Saint Lucie to Florida Keys bus services, operated by RedCoach, arrive at Miami Airport station.

Can I drive from Port Saint Lucie to Florida Keys?

Yes, the driving distance between Port Saint Lucie to Florida Keys is 259 miles. It takes approximately 5h 1m to drive from Port Saint Lucie to Florida Keys.

Where can I stay near Florida Keys?

There are 947+ hotels available in Florida Keys.

Port Saint Lucie to Florida Keys - 7 ways to travel via train, bus, and car

How to get fromPort Saint Lucie to Florida Keys

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There are 7 ways to get from Port Saint Lucie to Florida Keys by bus (Greyhound), car, bus, plane, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Fort Pierce to Miami Airportbus Orlando–Miami / ...
2. Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
8h 30m
$53–84
Drive 257.2 mi
cheapest
1. Drive from Port Saint Lucie to Florida Keyscar 257.2 mi
5h 1m
$47–68
Bus to Miami International Airport, fly
1. Take the bus from Fort Pierce to Miami Airportbus
2. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)plane MIA - EYW
7h 7m
$135–334
Bus, shuttle
1. Take the bus from Fort Pierce to Miami Airportbus Orlando–Miami / ...
2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle To the Keys
7h 57m
$183–224
Bus, train
1. Take the bus from Fort Pierce to Fort Lauderdale - Broward Blvd Park and Ridebus
2. Take the train from Fort Lauderdale Station to Miami Airport Stationtrain
3. Take the bus from Miami Airport Station to Big Pine Keybus
9h 13m
$56–88
Bus to Orlando, fly
1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus
2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
7h 17m
$172–798
Drive to Orlando Sanford, fly
1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar
2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
6h 40m
$136–379

Port Saint Lucie to Florida Keys by bus, tram, and foot

31Weekly Services

8h 30mAverage Duration

$53Cheapest Price

See schedules

Questions & Answers

Map of how to get from Port Saint Lucie to Florida Keys.

Launch map view

Distance: 260.7 mi
Duration: 8h 30m

What companies run services between Port Saint Lucie, FL, USA and Florida Keys, FL, USA?

You can take a bus from Fort Pierce to Florida Keys via Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 8h 30m.

Airlines

Train operators

Bus operators

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How to get fromPort Saint Lucie to Florida Keysby bus (Greyhound), car, bus, plane, shuttle, or train

There are 7 ways to get from Port Saint Lucie to Florida Keys by bus (Greyhound), car, bus, plane, shuttle, or train

Bus

Drive 257.2 mi

Bus to Miami International Airport, fly

Bus, shuttle

Bus, train

Bus to Orlando, fly

Drive to Orlando Sanford, fly