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How to get fromPort Saint Lucie to Gatlinburgby car, plane, taxi, bus, or train

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There are 9 ways to get from Port Saint Lucie to Gatlinburg by car, plane, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Mcghee Tyson Airport, taxi

    best
    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    3. Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi taxi
    5h 17m
    $304–895

  2. Drive to Orlando Sanford, fly to Asheville Regional Airport, drive

    cheapest
    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Drive from Asheville-Airport-AVL to Gatlinburgcar car
    6h 8m
    $94–398

  3. Bus, drive

    1. Take the bus from Fort Pierce to Orlandobus bus
    2. Take the bus from Orlando Bus Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Asheville, NCbus bus
    4. Drive from Asheville, NC to Gatlinburgcar car
    23h 50m
    $177–298

  4. Bus, train, drive

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Gatlinburgcar car
    26h 43m
    $295–592

  5. Drive 688.6 mi

    1. Drive from Port Saint Lucie to Gatlinburgcar car 688.6 mi
    14h 14m
    $126–182

  6. Bus to Orlando, fly to Mcghee Tyson Airport, taxi

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    3. Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi taxi
    7h 3m
    $304–853

  7. Bus to Fort Lauderdale–Hollywood International Airport, fly to Mcghee Tyson Airport, taxi

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Mcghee Tyson Airport (TYS)plane plane FLL - TYS
    3. Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi taxi
    6h 39m
    $331–953

  8. Bus to President Donald J. Trump International Airport, fly to Asheville Regional Airport, drive

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at BAY Dbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Asheville Regional Airport (AVL)plane plane PBI - AVL
    3. Drive from Asheville-Airport-AVL to Gatlinburgcar car
    7h 8m
    $130–497

  9. Bus to Fort Lauderdale–Hollywood International Airport, fly to Asheville Regional Airport, drive

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Asheville Regional Airport (AVL)plane plane FLL - AVL
    3. Drive from Asheville-Airport-AVL to Gatlinburgcar car
    7h 27m
    $116–446

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration1h 38mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Gatlinburg.ExpandLaunch map view
  • Distance: 682.1 mi
  • Duration: 5h 17m

What companies run services between Port Saint Lucie, FL, USA and Gatlinburg, TN, USA?

There is no direct connection from Port Saint Lucie to Gatlinburg. However, you can drive to Orlando-Sanford-Airport-SFB airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Gatlinburg. Alternatively, you can take a bus from Fort Pierce to Gatlinburg via L B Mcleod Rd & Gardenia Ave, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, Raleigh Bus Station, and Asheville, NC in around 23h 50m.

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