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How to get fromPort Saint Lucie to Greenvilleby bus, plane, bus (Flixbus), car, taxi, or bus (Greyhound)

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There are 9 ways to get from Port Saint Lucie to Greenville by bus, plane, bus (Flixbus), car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Fort Lauderdale–Hollywood International Airport, fly to Greenville–Spartanburg International Airport

    best
    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Greenville–Spartanburg International Airport (GSP)plane plane FLL - GSP
    5h 36m
    $206–888

  2. Drive 591.4 mi

    cheapest
    1. Drive from Port Saint Lucie to Greenvillecar car 591.4 mi
    11h 6m
    $108–156

  3. Bus

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus FlixBus N2401
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    15h 53m
    $177–351

  4. Drive to Orlando Sanford, fly to Asheville Regional Airport, taxi

    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    5h 9m
    $219–555

  5. Bus to President Donald J. Trump International Airport, fly to Asheville Regional Airport, taxi

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Asheville Regional Airport (AVL)plane plane PBI - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    6h 10m
    $255–651

  6. Bus to Miami International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Miami International Airport (MIA) to Greenville–Spartanburg International Airport (GSP)plane plane MIA - GSP
    6h 14m
    $163–639

  7. Bus to Fort Lauderdale–Hollywood International Airport, fly to Asheville Regional Airport, taxi

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Asheville Regional Airport (AVL)plane plane FLL - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    6h 28m
    $241–603

  8. Taxi to Vero Beach Municipal Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Charlotte Douglas International Airport (CLT)plane plane VRB - CLT
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    7h 40m
    $251–924

  9. Bus via Pembroke Pines

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Take the bus from Hollywood Sheridan Trirail Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    23h 11m
    $188–400

Fort Lauderdale–Hollywood International Airport (FLL) to Greenville–Spartanburg International Airport (GSP) flights

Calendar68Weekly Planes
Duration3h 32mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Greenville.ExpandLaunch map view
  • Distance: 736 mi
  • Duration: 5h 36m

What companies run services between Port Saint Lucie, FL, USA and Greenville, SC, USA?

You can take a vehicle from Port Saint Lucie to Greenville via Port St Lucie, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 15h 53m.

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